Wang M L, Hussey D H, Doornbos J F, Vigliotti A P, Wen B C
Division of Radiation Oncology, University of Iowa Hospitals and Clinics, Iowa City 52242.
Int J Radiat Oncol Biol Phys. 1988 Apr;14(4):643-8. doi: 10.1016/0360-3016(88)90084-3.
Between January 1950 and December 1981, 32 patients with chemodectomas of the temporal bone were treated at the University of Iowa Hospitals and Clinics. Thirteen patients were treated with surgery alone, 15 with radiation therapy alone, one with preoperative radiation therapy and surgery, and three with surgery and postoperative radiation therapy. In general, the patients treated with radiotherapy alone or combined therapy (radiotherapy group) had more advanced tumors than those treated with surgery alone (surgery group). For the surgery group, the initial local control rate was 46% and the ultimate local control rate 84% following salvage with additional surgery, 31% developed complications, and 78% survived 10 years. For the radiotherapy group, 84% had local tumor control, 11% developed complications, and 77% survived 10 years. These results demonstrate that radiation therapy is an effective treatment modality for chemodectomas of the temporal bone.
1950年1月至1981年12月期间，爱荷华大学医院及诊所共收治了32例颞骨化学感受器瘤患者。13例患者仅接受了手术治疗，15例仅接受了放射治疗，1例接受了术前放射治疗及手术，3例接受了手术及术后放射治疗。总体而言，单纯接受放射治疗或联合治疗的患者（放疗组）的肿瘤比单纯接受手术治疗的患者（手术组）更为晚期。对于手术组，初始局部控制率为46%，经额外手术挽救后的最终局部控制率为84%，31%出现并发症，78%存活10年。对于放疗组，84%实现了局部肿瘤控制，11%出现并发症，77%存活10年。这些结果表明，放射治疗是颞骨化学感受器瘤的一种有效治疗方式。
