Kakkar Naveen, Garg Geetu
Department of Pathology, Christian Medical College & Hospital, Ludhiana, Punjab.
Indian J Pathol Microbiol. 2006 Jan;49(1):29-31.
Automated platelet counts in the laboratory may be fictitiously low at times and require manual confirmation. Ethylenediaminetetra-acetic acid (EDTA) in few patients and healthy individuals can induce platelet aggregation, giving rise to a spuriously low automated platelet count. This phenomenon which occurs due to the presence of IgG antibodies, if unrecognized, can result in incorrect diagnosis and consequent inappropriate treatment. We present a patient who received inappropriate platelet transfusion as a result of EDTA induced spurious thrombocytopenia.
实验室中的自动血小板计数有时可能会虚假偏低,需要人工确认。少数患者和健康个体中的乙二胺四乙酸(EDTA)可诱导血小板聚集,导致自动血小板计数假性降低。这种由于IgG抗体的存在而出现的现象,如果未被识别,可能会导致错误诊断及随后的不恰当治疗。我们报告一例因EDTA诱导的假性血小板减少症而接受不恰当血小板输注的患者。