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乙二胺四乙酸(EDTA)诱导的假性血小板减少症患者的不适当血小板输注

Inappropriate platelet transfusion in a patient with ethylenediamine tetra- acetic acid (EDTA)--induced pseudothrombocytopenia.

作者信息

Kakkar Naveen, Garg Geetu

机构信息

Department of Pathology, Christian Medical College & Hospital, Ludhiana, Punjab.

出版信息

Indian J Pathol Microbiol. 2006 Jan;49(1):29-31.

PMID:16625970
Abstract

Automated platelet counts in the laboratory may be fictitiously low at times and require manual confirmation. Ethylenediaminetetra-acetic acid (EDTA) in few patients and healthy individuals can induce platelet aggregation, giving rise to a spuriously low automated platelet count. This phenomenon which occurs due to the presence of IgG antibodies, if unrecognized, can result in incorrect diagnosis and consequent inappropriate treatment. We present a patient who received inappropriate platelet transfusion as a result of EDTA induced spurious thrombocytopenia.

摘要

实验室中的自动血小板计数有时可能会虚假偏低,需要人工确认。少数患者和健康个体中的乙二胺四乙酸(EDTA)可诱导血小板聚集,导致自动血小板计数假性降低。这种由于IgG抗体的存在而出现的现象,如果未被识别,可能会导致错误诊断及随后的不恰当治疗。我们报告一例因EDTA诱导的假性血小板减少症而接受不恰当血小板输注的患者。

相似文献

1
Inappropriate platelet transfusion in a patient with ethylenediamine tetra- acetic acid (EDTA)--induced pseudothrombocytopenia.乙二胺四乙酸(EDTA)诱导的假性血小板减少症患者的不适当血小板输注
Indian J Pathol Microbiol. 2006 Jan;49(1):29-31.
2
[Studies of platelet aggregation in six cases of EDTA-dependent pseudothrombocytopenia].6例乙二胺四乙酸依赖性假性血小板减少症的血小板聚集研究
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Anticoagulant-induced pseudothrombocytopenia and pseudoleucocytosis.抗凝剂诱导的假性血小板减少症和假性白细胞增多症。
Thromb Haemost. 1995 Mar;73(3):506-13.
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EDTA-dependent pseudothrombocytopenia in a child.儿童的 EDTA 依赖性假性血小板减少症。
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[EDTA-dependent pseudo-thrombopenia].[乙二胺四乙酸依赖性假性血小板减少症]
Schweiz Med Wochenschr. 1986 Nov 8;116(45):1566-9.
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Transfusion medicine illustrated. Unnecessary transfusions due to pseudothrombocytopenia.图解输血医学。假性血小板减少导致的不必要输血。
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Effective estimation of correct platelet counts in pseudothrombocytopenia using an alternative anticoagulant based on magnesium salt.采用基于镁盐的替代抗凝剂有效估计假性血小板减少症中的正确血小板计数。
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[Pseudothrombocytopenia caused by ethylenediaminetetraacetic acid (EDTA) (case report)].[乙二胺四乙酸(EDTA)所致假性血小板减少症(病例报告)]
Lijec Vjesn. 1997 Jan;119(1):19-21.
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[EDTA-dependent pseudothrombocytopenia: clinical aspects and laboratory tests].[乙二胺四乙酸依赖性假性血小板减少症:临床特征与实验室检查]
Rinsho Byori. 2005 Jul;53(7):646-53.
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[Pseudothrombocytopenia caused by extraction of the blood using ethylenediaminetetraacetic acid (EDTA). A cause of diagnostic error].
Med Clin (Barc). 1985 May 11;84(18):738-9.

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