Nicholas Simon, Riley Andrew, Patel Hussain, Neveldson Bridget, Purdie Gordon, Wells Anthony P
Ophthalmology Department, Wellington Hospital, Wellington, New Zealand.
Clin Exp Ophthalmol. 2006 Mar;34(2):124-9; quiz 194. doi: 10.1111/j.1442-9071.2006.01169.x.
To investigate correlations between optical coherence tomography macular thickness measurements and visual acuity after cataract surgery.
Sixty-two patients underwent routine cataract surgery as part of a randomized clinical trial of oral Cox-2 inhibitor prophylaxis of cystoid macular oedema. Optical coherence tomography was used to quantify several parameters of macular thickness. Optical coherence tomography measurements were obtained before surgery, day one, week two and week six after surgery. These measurements were then correlated with logMAR best-corrected visual acuity.
Optical coherence tomography macular thickness parameters increased after surgery by up to 20%. A significant correlation was identified between foveal minimum macular thickness and best-corrected visual acuity at day one and week six after surgery. Other macular parameters failed to show any significant correlation. At day one and week six, the 10 patients with greatest macular thickness had significantly lower visual acuity than the other patients.
In this study routine cataract surgery caused an increase in macular thickness. Some significant positive correlations between macular thickness and best-corrected visual acuity were found, although not for all parameters or time points. There may be a threshold relationship between degree of foveal anatomic change and significant loss of visual acuity.
研究白内障手术后光学相干断层扫描黄斑厚度测量值与视力之间的相关性。
62例患者接受了常规白内障手术，这是一项口服Cox-2抑制剂预防黄斑囊样水肿的随机临床试验的一部分。使用光学相干断层扫描来量化黄斑厚度的几个参数。在手术前、术后第1天、第2周和第6周进行光学相干断层扫描测量。然后将这些测量值与logMAR最佳矫正视力进行相关性分析。
手术后光学相干断层扫描黄斑厚度参数增加了20%。在术后第1天和第6周，黄斑中心凹最小厚度与最佳矫正视力之间存在显著相关性。其他黄斑参数未显示出任何显著相关性。在术后第1天和第6周，黄斑厚度增加最多的10例患者的视力明显低于其他患者。
在本研究中，常规白内障手术导致黄斑厚度增加。发现黄斑厚度与最佳矫正视力之间存在一些显著的正相关，尽管并非所有参数或时间点均如此。黄斑中心凹解剖学变化程度与明显视力丧失之间可能存在阈值关系。
