I型干扰素的抗炎特性。
Anti-inflammatory properties of Type I interferons.
作者信息
Billiau Alfons
机构信息
Rega Institute, University of Leuven, Minderbroedersstraat 10, BE-3000 Leuven, Belgium.
出版信息
Antiviral Res. 2006 Sep;71(2-3):108-16. doi: 10.1016/j.antiviral.2006.03.006. Epub 2006 Apr 4.
Abstract
The notion that Type I interferons (interferon-alpha and -beta) possess anti-inflammatory potential is supported by data from clinical application in multiple sclerosis, by studies on cultured immune-competent cells and by investigation of experimental diseases in whole animals. These observations deserve the attention of virologists for their potential role in the pathogenesis and clinical management of virus infections.
摘要
I型干扰素（α干扰素和β干扰素）具有抗炎潜力这一观点，得到了来自多发性硬化症临床应用数据、对培养的免疫活性细胞的研究以及对整体动物实验性疾病的调查的支持。这些观察结果因其在病毒感染的发病机制和临床管理中的潜在作用，值得病毒学家关注。
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