Jolley Suzanne, Garety Philippa A, Ellett Lyn, Kuipers Elizabeth, Freeman Daniel, Bebbington Paul E, Fowler David G, Dunn Graham
King's College London, Department of Psychology, Institute of Psychiatry, Denmark Hill, UK.
Schizophr Res. 2006 Jul;85(1-3):288-95. doi: 10.1016/j.schres.2006.03.012. Epub 2006 Apr 19.
Despite demonstrated relationships between activity and clinical change, we lack effective measures of time use in psychosis. Existing time budget measures of activity are demanding to complete, and thus unsuited to routine clinical use as measures of change. Less burdensome 'check-box' measures are prone to bias and omission in the activities selected. We recently devised a simplified time budget measure of activity in psychosis which was piloted on a small sample [Jolly, S., Garety, P., Dunn, G., White, J., Aitken, M., Challocombe, F., Griggs, M., Wallace, M., Craig, T. 2005. A pilot validation study of a new measure of activity in psychosis. Soc. Psychiatry Psychiatr. Epidemiol. 40, 905-911]. This study is a larger scale validation. 276 participants with a recent relapse of non-affective psychosis completed the new time budget, together with an established measure of global social functioning, measures of positive and negative psychotic symptoms, positive symptom distress and affect. The time budget measure showed a correlation of 0.5 with both the SOFAS and the SANS avolition/apathy subscale. Activity levels were related to psychotic symptomatology, both positive and negative. Positive symptom distress was more strongly associated with activity levels than symptom severity and affective disturbance. We conclude that the time budget measure can be used as an indicator of social functioning, with potential as a measure of therapeutic change. We are currently investigating its sensitivity in this context.
尽管已证明活动与临床变化之间存在关联，但我们仍缺乏针对精神病患者时间利用情况的有效测量方法。现有的活动时间预算测量方法实施起来要求较高，因此不适合作为常规临床变化测量方法使用。负担较轻的“勾选式”测量方法在所选活动中容易出现偏差和遗漏。我们最近设计了一种简化的精神病患者活动时间预算测量方法，并在一个小样本上进行了试点[乔利，S.，加雷蒂，P.，邓恩，G.，怀特，J.，艾特肯，M.，查洛科姆，F.，格里格斯，M.，华莱士，M.，克雷格，T. 2005年。精神病患者活动新测量方法的试点验证研究。《社会精神病学与精神疾病流行病学》40卷，905 - 911页]。本研究是一项更大规模的验证。276名近期非情感性精神病复发的参与者完成了新的时间预算测量，同时还完成了一项既定的全球社会功能测量、阳性和阴性精神病症状测量、阳性症状困扰和情感测量。时间预算测量方法与社会功能评定量表（SOFAS）以及阴性症状评定量表（SANS）中的意志缺乏/淡漠分量表的相关性均为0.5。活动水平与阳性和阴性精神病症状学均相关。与症状严重程度和情感障碍相比，阳性症状困扰与活动水平的关联更强。我们得出结论，时间预算测量方法可作为社会功能的指标，具有作为治疗变化测量方法的潜力。我们目前正在研究其在这方面的敏感性。
