Freeman James V, Dewey Frederick E, Hadley David M, Myers Jonathan, Froelicher Victor F
Division of Cardiovascular Medicine, Stanford University Medical Center and Veterans Affairs Health Care System, Palo Alto, CA 94304, USA.
Prog Cardiovasc Dis. 2006 Mar-Apr;48(5):342-62. doi: 10.1016/j.pcad.2005.11.003.
There is considerable recent evidence that parameters thought to reflect the complex interaction between the autonomic nervous system and the cardiovascular system during exercise testing can provide significant prognostic information. Specific variables of great importance include heart rate (HR) response to exercise (reserve), HR recovery after exercise, and multiple components of HR variability both at rest and with exercise. Poor HR response to exercise has been strongly associated with sudden cardiac death and HR recovery from a standard exercise test has been shown to be predictive of mortality. In addition, there are limited studies evaluating the components of HR variability at rest and during exercise and their prognostic significance. Research continues seeking to refine these exercise measurements and further define their prognostic value. Future findings should augment the power of the exercise test in risk-stratifying cardiovascular patients.
最近有大量证据表明，在运动测试期间，那些被认为能反映自主神经系统与心血管系统之间复杂相互作用的参数，能够提供重要的预后信息。极为重要的特定变量包括运动时的心率（HR）反应（储备）、运动后的心率恢复，以及静息和运动时心率变异性的多个组成部分。运动时心率反应不佳与心源性猝死密切相关，并且标准运动测试后的心率恢复已被证明可预测死亡率。此外，评估静息和运动时心率变异性组成部分及其预后意义的研究有限。研究仍在继续，旨在完善这些运动测量方法，并进一步明确它们的预后价值。未来的研究结果应能增强运动测试在对心血管疾病患者进行风险分层方面的作用。
