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蓝舌病病毒和 epizootic hemorrhagic disease 病毒 VP3 的分子比较。

Molecular comparison of VP3 from bluetongue and epizootic hemorrhagic disease viruses.

作者信息

Wilson W C

机构信息

Agricultural Research Service, Arthropod-borne Animal Diseases Research Laboratory, Laramie, WY 82071.

出版信息

Virus Res. 1991 Nov;21(3):225-36. doi: 10.1016/0168-1702(91)90035-t.

DOI:10.1016/0168-1702(91)90035-t
PMID:1662848
Abstract

The complete nucleic acid sequence of gene 3 from epizootic hemorrhagic disease of deer (EHD) virus serotype 1 was determined. The 2768 bp sequence encodes a single protein that contains 899 amino acids and has a molecular weight of 103 kDa. The predicted protein sequence has 94.7% identity with EHD virus serotype 2 and greater than 77% identity with the related bluetongue viruses serotypes 1, 10 and 17 VP3 proteins. The relevance of these data to studies of recombinant DNA diagnostics and genetic relatedness is discussed.

摘要

测定了鹿流行性出血病病毒1型（EHDV-1）基因3的完整核酸序列。该2768 bp序列编码一种含有899个氨基酸、分子量为103 kDa的单一蛋白质。预测的蛋白质序列与EHD病毒2型有94.7%的同一性，与相关的蓝舌病毒1型、10型和17型VP3蛋白有超过77%的同一性。讨论了这些数据与重组DNA诊断和遗传相关性研究的相关性。

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