Wilson W C
USDA, Arthropod-borne Animal Diseases Research Laboratory, Laramie, WY 82071.
Virus Res. 1994 Oct;34(1):63-8. doi: 10.1016/0168-1702(94)90119-8.
The non-structural protein 2 (NS2) of epizootic hemorrhagic disease virus serotype 1 (EHD-1) was cloned and sequenced. The NS2 gene was found to be 1185 bp containing a single open reading frame that encodes a 376 amino acid protein. A 97% nucleic acid identity was found between EHD-1 and a previously published NS2 sequence of EHD-2. Only a 60% nucleic acid identity was found between EHD and the bluetongue virus (BTV) serogroup. Comparison of the deduced amino acid sequences revealed 97% identity within the EHD serogroup, and less than or equal to 43% identity between serogroups.
对1型流行性出血病病毒(EHD-1)的非结构蛋白2(NS2)进行了克隆和测序。发现NS2基因长度为1185 bp,包含一个单一的开放阅读框,编码一个由376个氨基酸组成的蛋白质。在EHD-1与先前发表的EHD-2的NS2序列之间发现了97%的核酸同一性。在EHD与蓝舌病病毒(BTV)血清群之间仅发现60%的核酸同一性。对推导的氨基酸序列进行比较,结果显示EHD血清群内的同一性为97%,血清群之间的同一性小于或等于43%。