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德克萨斯州埃尔帕索的本地获得性戊型肝炎病毒感染

Locally acquired hepatitis E virus infection, El Paso, Texas.

作者信息

Amon Joseph J, Drobeniuc Jan, Bower William A, Magaña Jorge C, Escobedo Miguel A, Williams Ian T, Bell Beth P, Armstrong Gregory L

机构信息

Epidemic Intelligence Service, Epidemiology Program Office, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA.

出版信息

J Med Virol. 2006 Jun;78(6):741-6. doi: 10.1002/jmv.20617.

DOI:10.1002/jmv.20617
PMID:16628579
Abstract

Hepatitis E virus (HEV) is an enterically transmitted RNA virus that causes both epidemic and sporadic cases of acute hepatitis. Despite sero-surveys showing antibody to HEV in up to 36% of the US population, acute hepatitis E has been reported among individuals with no history of international travel only three times in the United States. We report a case of apparently locally-acquired hepatitis E that occurred in El Paso, Texas that was 98% similar to a previously isolated HEV found in swine in the United States. Like the three previous cases, a thorough investigation found no conclusive sources of infection. Active case surveillance found no additional cases.

摘要

戊型肝炎病毒(HEV)是一种经肠道传播的RNA病毒,可导致急性肝炎的流行和散发病例。尽管血清学调查显示,美国高达36%的人群存在抗HEV抗体,但在美国,仅报告过3例无国际旅行史的急性戊型肝炎病例。我们报告了1例明显在当地感染的戊型肝炎病例,该病例发生在得克萨斯州的埃尔帕索,与之前在美国猪身上分离出的一种HEV有98%的相似性。与之前的3例病例一样,经过全面调查,未发现确凿的感染源。主动病例监测未发现其他病例。

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