Izadi H, Subrahmanyam B
Division of Plant Protection, Faculty of Agriculture, Valie Asr University, Rafsanjan, Iran.
Commun Agric Appl Biol Sci. 2005;70(4):651-60.
Insect growth regulatory activity (IGR) of fifty-two substituted oxime ethers were evaluated against an important polyphagous lepidopteran crop pest, Spodoptera litura (F.). A number of compounds produced symptoms comparable to exogenously applied juvenile hormone. Maximum IGR activity was exhibited by 4'-(2,6,6-trimethyl-2-cyclohexen- -yl)-3'-buten-2'(E)-ketoxime-N-O-alkyl ether with an ED50 (morphological) of 40 microg g(-1) body weight, compared to 20 microg g(-1) of JH III. Two more compounds namely 4'-(2,6,6-trimethyl-2-cyclohexen-1-yl)-3'-buten-2'(Z)-ketoxime-N-O-methyl propyl ether (ED50 192 microg g(-1)) and 4'-(2,6,6-trimethyl-1-cyclohexen-1-yl)-3'-buten-2'(E)-ketoxime-N-O-pentyl ether (ED50 380 microg g(-1)) showed considerable IGR activity, whereas 4'-(2,6,6-trimethyl-2-cyclohexen-1-yl)-3'-buten-2'(E)-ketoxime-N-O-pentyl ether was found to be toxic to the larvae (ED50 268 microg g(-1)). Three compounds used in this study were also synergised by piperonyl butoxide (PBO). The synergistic ratios were found in the range of 1.33 to 4.605. The ovicidal activity of the oxime ethers is not significant.
对52种取代肟醚针对一种重要的多食性鳞翅目作物害虫斜纹夜蛾（Spodoptera litura (F.)）进行了昆虫生长调节活性（IGR）评估。许多化合物产生了与外源施用保幼激素相当的症状。4'-(2,6,6-三甲基-2-环己烯-1-基)-3'-丁烯-2'(E)-酮肟-N-O-烷基醚表现出最大的IGR活性，其形态学半数有效剂量（ED50）为40微克/克体重，相比之下，保幼激素III的ED50为20微克/克体重。另外两种化合物，即4'-(2,6,6-三甲基-2-环己烯-1-基)-3'-丁烯-2'(Z)-酮肟-N-O-甲基丙基醚（ED50为192微克/克体重）和4'-(2,6,6-三甲基-1-环己烯-1-基)-3'-丁烯-2'(E)-酮肟-N-O-戊基醚（ED50为380微克/克体重）表现出相当可观的IGR活性，而4'-(2,6,6-三甲基-2-环己烯-1-基)-3'-丁烯-2'(E)-酮肟-N-O-戊基醚被发现对幼虫有毒（ED50为268微克/克体重）。本研究中使用的三种化合物也被胡椒基丁醚（PBO）增效。增效比在1.33至4.605范围内。肟醚的杀卵活性不显著。
