Lee Chunyong, Koike Michiaki, Oshimi Kazuo, Terakura Seitarou, Kodera Yositaka
Department of Hematology, Juntendo University, Shizuoka Hospital.
Rinsho Ketsueki. 2006 Mar;47(3):210-3.
In 2001, a 45-year-old man with severe aplastic anemia received a bone marrow transplantation from his HLA-identical sister, 2.5 years after which he developed severe liver dysfunction together with abdominal pain, disturbance of consciousness and generalized vesicles. Disseminated varicella-zoster virus infection was diagnosed by the detection of VZV DNA. Acyclovir and plasma exchange rapidly controlled his VZV-related symptoms and signs. Disseminated VZV infection is often fatal, but acyclovir and plasma exchange may be useful for such infection by reducing the circulating viral load.
2001年，一名45岁的严重再生障碍性贫血患者接受了来自其HLA配型相同的姐姐的骨髓移植，2.5年后，他出现了严重的肝功能障碍，伴有腹痛、意识障碍和全身性水疱。通过检测水痘带状疱疹病毒（VZV）DNA诊断为播散性水痘带状疱疹病毒感染。阿昔洛韦和血浆置换迅速控制了他与VZV相关的症状和体征。播散性VZV感染通常是致命的，但阿昔洛韦和血浆置换可能通过降低循环病毒载量对这种感染有用。
