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Two cases of varicella zoster virus meningitis found in pediatric patients after bone marrow transplantation despite valaciclovir prophylaxis and without skin lesions.

作者信息

Lévêque Nicolas, Galambrun Claire, Najioullah Fatiha, Bleyzac Nathalie, Pages Marie-Pierre, Bertrand Yves

机构信息

Laboratoire de virologie, Hôpital E. Herriot, Hospices civils de Lyon, Lyon, France.

出版信息

J Med Virol. 2006 Apr;78(4):514-6. doi: 10.1002/jmv.20570.

DOI:10.1002/jmv.20570
PMID:16482541
Abstract

Two cases of varicella zoster virus (VZV) meningitis are described in an 18-year-old girl and an 18-year-old boy. They occurred, respectively, 9 days and 9 months after allogeneic bone marrow transplantation. VZV nucleic acid was detected in the cerebrospinal fluid during the 1st week of illness. This recurrence occurred despite valaciclovir prophylaxis and without skin lesions. The two patients received aciclovir intravenously and immunoglobulins infusion. They responded to treatment and their clinical state improved rapidly.

摘要

相似文献

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Two cases of varicella zoster virus meningitis found in pediatric patients after bone marrow transplantation despite valaciclovir prophylaxis and without skin lesions.
J Med Virol. 2006 Apr;78(4):514-6. doi: 10.1002/jmv.20570.
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