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激励艾滋病毒呈阳性的女性坚持抗逆转录病毒治疗并采取降低风险行为:KHARMA项目。

Motivating HIV positive women to adhere to antiretroviral therapy and risk reduction behavior: the KHARMA Project.

作者信息

Holstad Marcia McDonnell, DiIorio Colleen, Magowe Mabel K M

机构信息

Family Community Health Department at the Nell Hodgson Woodruff School of Nursing at Emory University in Atlanta, Georgia, USA.

出版信息

Online J Issues Nurs. 2006 Jan 31;11(1):5.

PMID:16629499
Abstract

Women comprise the fastest growing group of persons with AIDS. They are often diagnosed later in the disease, when antiretroviral therapy (ART) is strongly indicated. Antiretroviral therapy has transformed the course of HIV/AIDS to a treatable, chronic illness. This article provides a profile of women with HIV/AIDS and describes ART. Selected research related to adherence and motivation is summarized. Psychosocial and economic concerns specific to women, ART, adherence, and motivation are presented. The article reviews challenges for risk reduction behaviors for HIV+ women, such as sexual activity and substance abuse. The authors discuss the Keeping Health and Active with Risk reduction and Medication Adherence (KHARMA) Project, a research project in progress that was designed to promote adherence to both ART and risk reduction behaviors in HIV+ women. The study includes two groups: a motivational group intervention based on motivational interviewing and a health promotion program control group tailored to the needs of HIV+ women. A description of the tailored intervention and project update is included.

摘要

女性是艾滋病患者中增长最快的群体。她们往往在疾病后期才被诊断出来,而此时强烈建议进行抗逆转录病毒治疗(ART)。抗逆转录病毒疗法已将艾滋病毒/艾滋病的病程转变为一种可治疗的慢性疾病。本文介绍了感染艾滋病毒/艾滋病的女性情况,并描述了抗逆转录病毒疗法。总结了与依从性和动机相关的部分研究。阐述了女性特有的心理社会和经济问题、抗逆转录病毒疗法、依从性及动机。文章回顾了艾滋病毒阳性女性在降低风险行为方面面临的挑战,如性行为和药物滥用。作者讨论了“通过降低风险和药物依从性保持健康与活力”(KHARMA)项目,这是一个正在进行的研究项目,旨在促进艾滋病毒阳性女性坚持抗逆转录病毒疗法和降低风险行为。该研究包括两组:一组是基于动机性访谈的动机性小组干预,另一组是根据艾滋病毒阳性女性需求定制的健康促进项目对照组。文中还包括了定制干预措施的描述和项目进展情况。

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