Mahalingam M, Kveaton J F, Bhawan J
UMass Memorial Medical Center, Memorial Campus, Worcester, MA 01605, USA.
J Cutan Pathol. 2006 Apr;33(4):315-7. doi: 10.1111/j.0303-6987.2006.00445.x.
Cutaneous neuroendocrine neoplasms are typically malignant. Benign cutaneous neuroendocrine tumors are uncommon.
We report the case of a 32-year-old female who presented with a granular mass in the right external auditory canal.
Microscopic examination of a shave biopsy revealed a poorly circumscribed neoplasm with glandular differentiation. While cytologic atypia and mitotic activity were not evident, pagetoid spread was observed. Immunohistochemistry was indicative of neuroendocrine origin.
This case report of neuroendocrine adenoma indicates that this entity should be entertained in the repertoire of conditions affecting the external ear.
