Gerardu Véronique, Heijnsbroek Muriel, Buijs Mark, van der Weijden Fridus, Ten Cate Bob, van Loveren Cor
Department of Cariology Endodontology Pedodontology, Academic Centre for Dentistry Amsterdam (ACTA), the Netherlands.
Eur J Oral Sci. 2006 Apr;114(2):128-32. doi: 10.1111/j.1600-0722.2006.00345.x.
Clinpro Cario L-Pop (CCLP) is a semiquantitive test claimed to determine the general potential for caries development and to monitor the individual caries risk. This test translates the capacity of the tongue microflora to produce lactic acid into a score of 1-9, indicating a low, medium or high risk for caries development. The aim of this randomized crossover, clinical trial was to evaluate the CCLP on its variation over time and its capacity to monitor the effect of three different oral hygiene procedures. The CCLP readings were compared with measurements of lactic acid in tongue biofilm and plaque samples by capillary ion electrophoresis (CIA). After four washout periods, the distribution of scores in the low-, medium-, and high-risk categories was 10%, 16%, and 74%, respectively. Out of 30 subjects, 11 scored consistently in the same category. The coefficients of variance of lactic acid concentrations were 31% for tongue samples and 25% for plaque samples. After using antimicrobial toothpaste and mouthwash, the number of high-risk scores was reduced to 33%; reduced acidogenicity was also found in tongue and plaque samples. We conclude that CCLP can be used to monitor and stimulate compliance to an antimicrobial oral hygiene protocol.
Clinpro Cario L-Pop（CCLP）是一种半定量检测方法，据称可确定龋齿发展的总体可能性并监测个体龋齿风险。该检测将舌部微生物群产生乳酸的能力转化为1至9分的评分，表明龋齿发展的低、中或高风险。这项随机交叉临床试验的目的是评估CCLP随时间的变化情况及其监测三种不同口腔卫生程序效果的能力。通过毛细管离子电泳（CIA）将CCLP读数与舌部生物膜和牙菌斑样本中乳酸的测量值进行比较。经过四个洗脱期后，低、中、高风险类别的评分分布分别为10%、16%和74%。在30名受试者中，有11人的评分始终处于同一类别。舌部样本中乳酸浓度的变异系数为31%，牙菌斑样本为25%。使用抗菌牙膏和漱口水后，高风险评分的数量降至33%；在舌部和牙菌斑样本中也发现产酸能力降低。我们得出结论，CCLP可用于监测并促进对抗菌口腔卫生方案的依从性。
