Marnera Georgia, d'Alarcao Marc
Department of Chemistry, Michael Research Building, Tufts University, Medford, MA 02155, USA.
Carbohydr Res. 2006 Jul 3;341(9):1105-16. doi: 10.1016/j.carres.2006.03.031. Epub 2006 Apr 21.
All six isomeric D-galactosaminopyranosyl-D-chiro-inositols have been prepared by glycosylation of appropriate penta-O-benzyl-D-chiro-inositols. The three requisite protected D-chiro-inositols were prepared by SmI2-promoted pinacol coupling of dialdehydes derived ultimately from L-arabinose.
所有六种异构的D-半乳糖胺基吡喃糖基-D-手性肌醇均通过适当的五-O-苄基-D-手性肌醇的糖基化反应制备而成。三种所需的受保护的D-手性肌醇是通过SmI2促进的最终源自L-阿拉伯糖的二醛的频哪醇偶联反应制备的。
