蛋白质合成起始过程中mRNA的两步选择
Two-step selection of mRNAs in initiation of protein synthesis.
作者信息
Hauryliuk Vasili, Ehrenberg Mans
机构信息
Department of Cell and Molecular Biology, Uppsala Universitet, BMC, S-75124 Uppsala, Sweden.
出版信息
Mol Cell. 2006 Apr 21;22(2):155-6. doi: 10.1016/j.molcel.2006.04.004.
PMID:16630885
Abstract
In a recent issue of Molecular Cell, Studer and Joseph (2006) clarified the molecular basis of the "standby model" and demonstrated how two-step binding of mRNAs to the small ribosomal subunit depends on initiator tRNA and initiation factors, with far-reaching implications for posttranscriptional regulation of gene expression.
摘要
在最近一期的《分子细胞》杂志上，施图德和约瑟夫（2006年）阐明了“备用模型”的分子基础，并展示了mRNA与小核糖体亚基的两步结合如何依赖于起始tRNA和起始因子，这对基因表达的转录后调控具有深远影响。
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