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一名持续性非卧床腹膜透析(CAPD)患者发生孤立性布鲁氏菌性腹膜炎。

Isolated Brucella peritonitis in a CAPD patient.

作者信息

Ozisik Lale, Akman Beril, Huddam Bulent, Azap Ozlem Kurt, Bilgic Ayse, Sezer Siren, Ozdemir Nurhan

机构信息

Department of Internal Medicine, Baskent University Faculty of Medicine, Ankara, Turkey.

出版信息

Am J Kidney Dis. 2006 May;47(5):e65-6. doi: 10.1053/j.ajkd.2006.01.028.

Abstract

Peritonitis is the most common complication in patients undergoing continuous ambulatory peritoneal dialysis (CAPD). Brucellosis is a rare cause of bacterial peritonitis. Only 1 case was reported of a patient with brucella peritonitis during CAPD therapy. In that case, CAPD peritonitis was accompanied by acute brucellosis. We present the case of a patient with isolated brucella peritonitis receiving CAPD therapy without systemic manifestations of brucellosis who works as a farmer. Results of a serum agglutination test and blood cultures were negative; however, the patient's peritoneal fluid agglutination titer was 1:160 and samples inoculated into BACTEC (Becton Dickinson, NJ) bottles yielded Brucella melitensis. Because we were unable to isolate the organism in blood samples, transmission seems to be the result of direct inoculation, rather than hematogenous spreading. Therefore, our patient represents the first case of isolated brucella peritonitis during CAPD therapy. Successful treatment was obtained by using a treatment regimen of rifampin and doxycycline.

摘要

腹膜炎是持续性非卧床腹膜透析(CAPD)患者最常见的并发症。布鲁氏菌病是细菌性腹膜炎的罕见病因。CAPD治疗期间仅有1例布鲁氏菌性腹膜炎患者的报道。在该病例中,CAPD腹膜炎伴有急性布鲁氏菌病。我们报告1例从事农民工作的接受CAPD治疗的孤立性布鲁氏菌性腹膜炎患者,其无布鲁氏菌病的全身表现。血清凝集试验和血培养结果均为阴性;然而,患者的腹腔积液凝集效价为1:160,接种于BACTEC(美国新泽西州Becton Dickinson公司)瓶中的样本培养出羊种布鲁氏菌。由于我们未能在血样中分离出该病原体,传播似乎是直接接种的结果,而非血行播散。因此,我们的患者代表了CAPD治疗期间首例孤立性布鲁氏菌性腹膜炎病例。通过使用利福平和强力霉素的治疗方案获得了成功治疗。

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