Schwetz Ines, Horina Jörg, Buzina Walter, Roob Johannes, Olschewski Horst, Krause Robert
Department of Pulmonology, Division of Infectious Diseases, Medical University of Graz, Austria.
Am J Kidney Dis. 2007 May;49(5):701-4. doi: 10.1053/j.ajkd.2007.02.260.
Fungal peritonitis is a rare, but serious, complication of continuous ambulatory peritoneal dialysis (CAPD). We report a case of peritonitis caused by Aspergillus oryzae in a man on CAPD therapy who was treated successfully with amphotericin B and caspofungin, followed by itraconazole and removal of the peritoneal catheter. A oryzae was identified by using sequence analysis of the ribosomal DNA genes. Of 10 reported cases since 2003, the mortality rate was 30%. Removal of the CAPD catheter and systemic antimycotic therapy are essential to achieve clinical cure in patients with fungal CAPD-related peritonitis.
真菌性腹膜炎是持续性非卧床腹膜透析（CAPD）一种罕见但严重的并发症。我们报告一例CAPD治疗男性患者发生米曲霉引起的腹膜炎，该患者接受两性霉素B和卡泊芬净成功治疗，随后使用伊曲康唑并拔除腹膜导管。通过核糖体DNA基因序列分析鉴定出米曲霉。自2003年以来报告的10例病例中，死亡率为30%。对于真菌性CAPD相关腹膜炎患者，拔除CAPD导管和全身抗真菌治疗是实现临床治愈的关键。
