Cornaggia Cesare Maria, Beghi Massimiliano, Moltrasio Luca, Beghi Ettore
Clinica Psichiatrica, Università di Milano-Bicocca, Via Cadore 48, 20052 Monza (Milano), Italy.
Seizure. 2006 Jul;15(5):313-9. doi: 10.1016/j.seizure.2006.03.001. Epub 2006 Apr 24.
Studies on accidents at work in people with epilepsy are scarce and the evidence that epilepsy carries an increased risk of accidents at work is mostly anecdotal. The present survey is a multicentre prospective cohort study of everyday life risks recently conducted in eight European countries (Estonia, Germany, Italy, the Netherlands, Portugal, Russia, Slovenia and United Kingdom) comparing referral children and adults with epilepsy to age- and sex-matched non-epileptic controls. In this context, every accident occurring during work over a 1-3 year follow-up was prospectively reported by patients and controls. Six hundred and thirty-one adult patients with epilepsy and 592 controls from this cohort have been studied here. Each patient and his/her control received a diary to record any accident or illness, with severity, circumstances, causes, consequences (including days off-work) and (for the cases) the possible relation to a seizure. A slightly higher number of unskilled workers were present among patients with epilepsy than in controls. Twenty-two patients with epilepsy and nine controls reported accidents during work (p<0.05). Only two cases reported seizure-related accidents. In both groups the injuries were mild (only one requiring hospitalization) and caused abstention from work to the same extent. In patients with epilepsy, the risk of accidents was unaffected by seizure type and frequency. This study confirms that patients with epilepsy are at higher risk of accidents compared to the general population. However, injuries provoked by work accidents are generally mild and unrelated to seizures.
关于癫痫患者工作事故的研究很少，而且癫痫会增加工作事故风险的证据大多是传闻。本次调查是一项多中心前瞻性队列研究，近期在八个欧洲国家（爱沙尼亚、德国、意大利、荷兰、葡萄牙、俄罗斯、斯洛文尼亚和英国）开展，将转诊的癫痫儿童和成人与年龄及性别匹配的非癫痫对照者进行比较。在此背景下，患者和对照者前瞻性报告了在1至3年随访期间工作中发生的每起事故。本研究纳入了该队列中的631名成年癫痫患者和592名对照者。每位患者及其对照者都收到一本日记，用于记录任何事故或疾病，包括严重程度、情况、原因、后果（包括缺勤天数）以及（对于病例）与癫痫发作的可能关系。癫痫患者中从事非技术工作的人数略高于对照者。22名癫痫患者和9名对照者报告了工作期间的事故（p<0.05）。只有两例报告了与癫痫发作相关的事故。两组中的损伤均较轻（仅1例需要住院治疗），且导致的缺勤程度相同。在癫痫患者中，事故风险不受癫痫发作类型和频率的影响。这项研究证实，与普通人群相比，癫痫患者发生事故的风险更高。然而，工作事故引发的损伤通常较轻，且与癫痫发作无关。
