Greening Jane
Department of Physiology, University College London, Gower Street, London WC1E 6BT, UK.
Man Ther. 2006 Aug;11(3):171-2. doi: 10.1016/j.math.2006.03.001. Epub 2006 Apr 24.
Nerve sheath inflammation without significant axonal degeneration can result in c fibres (both axons in continuity and the nervi nervorum) becoming spontaneously active and mechanically sensitive. This may help explain the painful responses when examining neural dynamics in patients with non specific arm pain, carpal tunnel syndrome and arm pain following whiplash injury, when longitudinal nerve excursion (measured using ultrasound imaging), appears to be within normal ranges. These findings have implications for the clinical examination and treatment of these patients groups.
无明显轴突变性的神经鞘炎症可导致C纤维(包括连续的轴突和神经束膜神经)自发激活并对机械刺激敏感。这或许有助于解释在检查非特异性手臂疼痛、腕管综合征以及挥鞭伤后手臂疼痛患者的神经动力学时出现的疼痛反应,此时纵向神经移位(使用超声成像测量)似乎在正常范围内。这些发现对这些患者群体的临床检查和治疗具有启示意义。