Watts J L, Saigal S
Department of Pediatrics, McMaster University, 1200 Main St W, HSC-3N27, Hamilton, Ontario L8S 4J9, Canada.
Arch Dis Child Fetal Neonatal Ed. 2006 May;91(3):F221-5. doi: 10.1136/adc.2005.071928.
Application of technology in neonatal intensive care has been very successful in reducing mortality, particularly in extremely low birthweight infants. As survival has improved, the need for accurate studies of long term outcome has increased. This need has been met by studies that are larger, more inclusive, and address a wider variety of later outcomes. Rather than a comprehensive quantitative review of these studies, this article uses a smaller number of studies that focus on infants of borderline viability, to illustrate current dilemmas and challenges in interpretation, and the actions, both individual and societal, that may be prompted by these interpretations.
技术在新生儿重症监护中的应用在降低死亡率方面非常成功,尤其是对于极低出生体重儿。随着存活率的提高,对长期预后进行准确研究的需求也增加了。规模更大、包容性更强且涉及更广泛后期结局的研究满足了这一需求。本文并非对这些研究进行全面的定量综述,而是使用较少数量的聚焦于临界生存能力婴儿的研究,来说明当前在解读方面的困境和挑战,以及这些解读可能促使个人和社会采取的行动。