Division of Newborn Medicine, Children's Hospital Boston, Boston, MA, USA.
Paediatr Perinat Epidemiol. 2013 Mar;27(2):199-207. doi: 10.1111/ppe.12025. Epub 2012 Dec 10.
Former preterm and very low birthweight infants require close neurodevelopmental surveillance after hospital discharge, but in-person professional testing is resource-intensive and inconvenient for families. A standardised developmental questionnaire completed by parents offers an alternative to in-person testing, but few such questionnaires have been validated. Our aim was to validate the Motor and Social Development (MSD) scale in a sample of former preterm infants.
We studied 321 visits to a neonatal follow-up clinic. Parents completed the MSD, which measures cognitive, motor and social abilities. Psychologists and physical therapists administered the Bayley Scales of Infant Development, 3rd edition (Bayley-III) cognitive and motor scales.
The median (range) gestational age was 28 (23, 34) weeks and birthweight 980 (400, 2700) g. Corrected age at study participation ranged 5-35 months. The mean (standard deviation) Bayley-III motor score was 94 (16), cognitive 98 (16) and MSD 91 (18). Internal consistency of the MSD was moderate to high (Cronbach alpha of 0.65 to 0.88). The MSD was moderately correlated with the Bayley-III motor (Pearson r = 0.49, P < 0.001) and cognitive (r = 0.45, P < 0.001) scales. The area under the receiver operating characteristic curve was 0.88 [95% confidence interval (CI) 0.81, 0.95] for the MSD to detect a low Bayley-III motor score (<70), and 0.88 [95% CI 0.82, 0.95] for a low cognitive score, indicating good discrimination.
The MSD has good internal and concurrent validity, and may be useful for neurodevelopmental assessment of former preterm and very low birthweight infants in clinical and research settings.
既往早产和极低出生体重儿出院后需要密切的神经发育监测，但面对面的专业测试对家庭来说资源密集且不便。家长填写标准化发育问卷是一种替代面对面测试的方法，但很少有此类问卷经过验证。我们的目的是在既往早产婴儿样本中验证运动和社会发育量表（MSD）的有效性。
我们研究了 321 次新生儿随访诊所就诊。家长填写 MSD，该量表测量认知、运动和社会能力。心理学家和物理治疗师进行贝利婴幼儿发展量表，第三版（Bayley-III）认知和运动量表测试。
中位（范围）胎龄为 28（23，34）周，出生体重为 980（400，2700）g。研究时的校正年龄为 5-35 个月。Bayley-III 运动评分的平均值（标准差）为 94（16），认知评分为 98（16），MSD 为 91（18）。MSD 的内部一致性为中等到高度（Cronbach 阿尔法为 0.65 至 0.88）。MSD 与 Bayley-III 运动（Pearson r=0.49，P<0.001）和认知（r=0.45，P<0.001）评分中度相关。MSD 检测低 Bayley-III 运动评分（<70）的受试者工作特征曲线下面积为 0.88（95%置信区间，0.81，0.95），检测低认知评分的面积为 0.88（95%置信区间，0.82，0.95），表明具有良好的区分度。
MSD 具有良好的内部和同时有效性，可用于临床和研究环境中既往早产和极低出生体重儿的神经发育评估。
