• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Controlling the cytokine storm by insulin: glycogen synthase kinase-3 as a target in systemic inflammation.

作者信息

Mühl Heiko, Pfeilschifter Josef

出版信息

Crit Care Med. 2006 May;34(5):1567-9. doi: 10.1097/01.CCM.0000216192.11019.46.

DOI:10.1097/01.CCM.0000216192.11019.46
PMID:16633265
Abstract
摘要

相似文献

1
Controlling the cytokine storm by insulin: glycogen synthase kinase-3 as a target in systemic inflammation.
Crit Care Med. 2006 May;34(5):1567-9. doi: 10.1097/01.CCM.0000216192.11019.46.
2
Insulin reduces the multiple organ injury and dysfunction caused by coadministration of lipopolysaccharide and peptidoglycan independently of blood glucose: role of glycogen synthase kinase-3beta inhibition.胰岛素可减轻脂多糖和肽聚糖联合给药所致的多器官损伤和功能障碍，且独立于血糖：糖原合酶激酶-3β抑制的作用
Crit Care Med. 2006 May;34(5):1489-96. doi: 10.1097/01.CCM.0000215457.83953.E3.
3
Glycogen synthase kinase-3beta inhibition attenuates asthma in mice.糖原合酶激酶-3β抑制可减轻小鼠哮喘症状。
Am J Respir Crit Care Med. 2007 Sep 1;176(5):431-8. doi: 10.1164/rccm.200609-1292OC. Epub 2007 Jun 7.
4
Glycogen synthase kinase 3beta as a target for the therapy of shock and inflammation.糖原合酶激酶3β作为休克和炎症治疗的靶点。
Shock. 2007 Feb;27(2):113-23. doi: 10.1097/01.shk.0000238059.23837.68.
5
Glycogen synthase kinase-3 beta inhibitor suppresses Porphyromonas gingivalis lipopolysaccharide-induced CD40 expression by inhibiting nuclear factor-kappa B activation in mouse osteoblasts.糖原合酶激酶-3β抑制剂通过抑制核因子-κB 活化抑制牙龈卟啉单胞菌脂多糖诱导的小鼠成骨细胞 CD40 表达。
Mol Immunol. 2012 Aug;52(1):38-49. doi: 10.1016/j.molimm.2012.04.005. Epub 2012 May 14.
6
Novel heterocycle-substituted pyrimidines as inhibitors of NF-kappaB transcription regulation related to TNF-alpha cytokine release.
Bioorg Med Chem Lett. 2008 Jan 15;18(2):653-6. doi: 10.1016/j.bmcl.2007.11.064. Epub 2007 Nov 22.
7
Flavonoid apigenin modified gene expression associated with inflammation and cancer and induced apoptosis in human pancreatic cancer cells through inhibition of GSK-3β/NF-κB signaling cascade.黄酮类芹菜素通过抑制GSK-3β/NF-κB信号级联反应来改变与炎症和癌症相关的基因表达，并诱导人胰腺癌细胞凋亡。
Mol Nutr Food Res. 2013 Dec;57(12):2112-27. doi: 10.1002/mnfr.201300307. Epub 2013 Aug 14.
8
Inhibition of glycogen synthase kinase-3β by lithium chloride suppresses 6-hydroxydopamine-induced inflammatory response in primary cultured astrocytes.氯化锂抑制糖原合酶激酶-3β抑制原代培养星形胶质细胞中 6-羟多巴胺诱导的炎症反应。
Neurochem Int. 2013 Nov;63(5):345-53. doi: 10.1016/j.neuint.2013.07.003. Epub 2013 Jul 16.
9
Inhibiting glycogen synthase kinase 3beta in sepsis.抑制脓毒症中的糖原合酶激酶3β
Novartis Found Symp. 2007;280:128-42; discussion 142-6, 160-4.
10
What do insulin, estrogen, valproic acid, and TDZD-8 have in common?胰岛素、雌激素、丙戊酸和TDZD - 8有什么共同之处？
Crit Care Med. 2005 Sep;33(9):2115-7. doi: 10.1097/01.ccm.0000178348.82829.ad.

引用本文的文献

1
Beneficial and detrimental effects of plasmin(ogen) during infection and sepsis in mice.纤溶酶（原）在感染和脓毒症小鼠中的有益和有害作用。
PLoS One. 2011;6(9):e24774. doi: 10.1371/journal.pone.0024774. Epub 2011 Sep 12.
2
Staphylococcus aureus induces microglial inflammation via a glycogen synthase kinase 3beta-regulated pathway.金黄色葡萄球菌通过糖原合酶激酶3β调控的途径诱导小胶质细胞炎症。
Infect Immun. 2009 Sep;77(9):4002-8. doi: 10.1128/IAI.00176-09. Epub 2009 Jul 13.
3
Glycogen synthase kinase-3 negatively regulates anti-inflammatory interleukin-10 for lipopolysaccharide-induced iNOS/NO biosynthesis and RANTES production in microglial cells.
糖原合成酶激酶-3负调控抗炎性白细胞介素-10，抑制脂多糖诱导的小胶质细胞中诱导型一氧化氮合酶/一氧化氮合成和 RANTES 产生。
Immunology. 2009 Sep;128(1 Suppl):e275-86. doi: 10.1111/j.1365-2567.2008.02959.x. Epub 2008 Oct 29.
4
Bioinformatics analysis of the early inflammatory response in a rat thermal injury model.大鼠热损伤模型早期炎症反应的生物信息学分析
BMC Bioinformatics. 2007 Jan 10;8:10. doi: 10.1186/1471-2105-8-10.