Yamanaka Hisashi, Tohma Shigeto
Institute of Rheumatology, Tokyo Women's Medical University, 10-22 Kawada-cho, Shinjuku-ku, Tokyo, 162-0054, Japan.
Mod Rheumatol. 2006;16(2):75-6. doi: 10.1007/s10165-006-0464-8.
For better management of rheumatoid arthritis (RA) patients, we need information both from well-designed clinical trials, such as randomized controlled trials, and from observational cohorts. Observational cohort study has not been developed in Japanese RA patients; however, two cohorts, IORRA (formerly J-ARAMIS) from 2000 and NinJa by iR-net from 2002, have been established. These two cohorts are an important source not only for better management of Japanese RA patients but also for solutions to a variety of issues concerning RA clinical practice in general. In this minireview, necessities of observational cohort studies are discussed.
为了更好地管理类风湿关节炎（RA）患者，我们既需要来自精心设计的临床试验（如随机对照试验）的信息，也需要来自观察性队列研究的信息。日本的RA患者尚未开展观察性队列研究；然而，已经建立了两个队列，分别是2000年的IORRA（原名J-ARAMIS）和2002年iR-net的NinJa。这两个队列不仅是更好地管理日本RA患者的重要来源，也是解决一般RA临床实践中各种问题的重要来源。在本综述中，讨论了观察性队列研究的必要性。
