Molnár Márk, Csuhaj Roland, Horváth Szabolcs, Vastagh Ildikó, Gaál Zsófia Anna, Czigler Balázs, Bálint Andrea, Nagy Zoltán
Magyar Tudományos Akadémia, Pszichológiai Kutatóintézet, Budapest.
Ideggyogy Sz. 2006 Mar 20;59(3-4):121-31.
Although the EEG-changes caused by ischemic stroke are well known, data of the literature are rather ambiguous. The EEG-findings recorded in a patient with a unilateral subcortical ischemic lesion are evaluated with special emphasis related to the effect of the dynamics caused by eye opening.
Data recorded from a patient (54 years old male with a completed stroke involving the frontal and parietal subcortical region in the left side) were compared to those of a control group (12 healthy age matched subjects). Absolute and relative frequency spectra, theta/beta quotients, the interaction index characterizing the effect of eyes opening and the symmetry index were calculated from the EEG recorded in eyes closed and eyes open conditions. Data of the patient were compared to those recorded in the control group on the basis of 95% confidence intervals.
Irrespective of the recording conditions the predominance of slow activity and the increase of theta/beta quotients were found in the absolute frequency spectra. The increase of beta and beta2 frequency bands following eye opening on the side of the lesion were found to be less obvious than that seen on the intact side and that observed in the control group. With respect to the interaction index related to the side differences caused by eye opening the change of the beta2 frequency band was found to be the most conspicuouS. The symmetry index underscored the predominance of slow (delta, theta, alpha1) frequencies on the lesion side, and that of the fast (beta1, beta2) frequencies on the intact side in both recording conditions.
Localized lesion of the white matter without cortical damage can cause the predominance of slow activity and decrease of the fast frequency bands on the side of the lesion which can be shown by the absolute frequency spectra and is revealed by the symmetry index. The lack of functional reactivity of the fast frequencies in the side of the lesion can clearly be seen in the change of relative spectra following eye opening and on the basis of the calculation of the interaction index reflecting the dynamics of side differences.
尽管缺血性中风引起的脑电图变化已为人熟知，但文献数据却相当模糊。对一名患有单侧皮质下缺血性病变患者记录的脑电图结果进行评估，特别强调睁眼引起的动态变化的影响。
将一名患者（54岁男性，左侧额叶和顶叶皮质下区域发生完全性中风）记录的数据与对照组（12名年龄匹配的健康受试者）的数据进行比较。从闭眼和睁眼状态下记录的脑电图中计算绝对和相对频谱、θ/β商、表征睁眼效应的相互作用指数以及对称指数。根据95%置信区间将患者的数据与对照组记录的数据进行比较。
无论记录条件如何，在绝对频谱中均发现慢波活动占优势且θ/β商增加。发现病变侧睁眼后β和β2频段的增加不如健侧以及对照组明显。关于与睁眼引起的侧别差异相关的相互作用指数，发现β2频段的变化最为显著。对称指数强调在两种记录条件下，病变侧慢波（δ、θ、α1）频率占优势，而健侧快波（β1、β2）频率占优势。
无皮质损伤的白质局部病变可导致病变侧慢波活动占优势以及快波频段减少，这可通过绝对频谱显示并由对称指数揭示。病变侧快波频率缺乏功能反应性在睁眼后的相对频谱变化以及基于反映侧别差异动态变化的相互作用指数计算中清晰可见。
