Akçam Mustafa, Yilmaz Aygen
Department of Pediatrics, Faculty of Medicine, Süleyman Demirel University, Isparta, Turkey.
Pediatr Int. 2006 Apr;48(2):125-7. doi: 10.1111/j.1442-200X.2006.02182.x.
Safe and effective treatment of infantile colic (IC) has not yet been determined. In this study, the authors aimed to investigate the efficiency of 30% glucose solution in the treatment of IC.
A total of 25 infants diagnosed as typical IC were given 1 mL of 30% glucose solution or sterile water for 4 days consecutively, in a randomized, double blind crossover trial. The effect was measured by parents' scoring.
Parents reported varying degrees of improvement in 16 infants (64%) given glucose solution, and in 12 infants (48%) given placebo. Comparison of treatment modalities were statistically significant (P = 0.031). There was no side-effect during treatments.
The present study revealed that 30% glucose was effective in the treatment of IC. Since oral glucose solution is natural, safe, cheap and easily achievable, it might be considered as an alternative therapy.
婴儿腹绞痛（IC）的安全有效治疗方法尚未确定。在本研究中，作者旨在探讨30%葡萄糖溶液治疗IC的疗效。
在一项随机、双盲交叉试验中，共有25名被诊断为典型IC的婴儿连续4天每天服用1毫升30%葡萄糖溶液或无菌水。疗效通过家长评分来衡量。
家长报告称，服用葡萄糖溶液的16名婴儿（64%）有不同程度的改善，服用安慰剂的12名婴儿（48%）有改善。治疗方式的比较具有统计学意义（P = 0.031）。治疗期间无副作用。
本研究表明30%葡萄糖对IC治疗有效。由于口服葡萄糖溶液天然、安全、便宜且易于获得，它可被视为一种替代疗法。
