[The rule of proliferation after sciatic injury of rats: immunohistological observation].

OBJECTIVE

To describe the rule of the schwann cell proliferation after peripheral nerve injury in detail and to discover the effect of neuroanastomosis.

METHODS

The model of rat sciatic injury was made, with neuroanastomosis on the left side and right side untreated. Then draw the materials 24, 48 h, 4, 7, 14, 21 d after surgery. And immunohistological stain counted the schwann cell per view with Qwin software of Leica Ltd.

RESULTS

The number of schwann cell increased obviously 4 d after surgery and reached the peak in 7 d. Then it fell down and the neuroanastomosis group changed slower and fibroblast hyperplasia in the untreated.

CONCLUSIONS

The axon support is essential for the schwann cell. The precise rule is help for study on neurotrophic factor.