Parsons Trisha L, Toffelmire Edwin B, King-VanVlack Cheryl E
School of Rehabilitation Therapy, Queen's University, and Division of Nephrology, Kingston General Hospital, ON, Canada.
Arch Phys Med Rehabil. 2006 May;87(5):680-7. doi: 10.1016/j.apmr.2005.12.044.
To determine the impact of a 20-week intradialytic exercise program, consisting of 60 minutes of cumulative duration, low-intensity exercise during the first 2 hours of dialysis, on dialysis efficacy, physical performance, and quality of life in self-care hemodialysis (HD) patients.
One-group repeated measures.
Satellite HD units affiliated with a Canadian teaching hospital.
A convenience sample of 13 self-care HD patients who were stable on dialysis for a minimum of 6 months and were medically screened for significant cardiac, pulmonary, and/or musculoskeletal pathology that would preclude exercise.
A 5-month intradialytic exercise program in which subjects exercised 3 times a week (cycle ergometer, mini-stepper) for 30 minutes in each of the first 2 hours of HD.
Dialysis efficacy (in single-pool model of urea kinetics [spKt/V]) was assessed prior to and at the end of each month of the exercise program. Physical function (6-minute walk test [6MWT]), and quality of life. (Kidney Disease Quality of Life-Short Form [KDQOL]) were determined at baseline and at weeks 10 and 20 of the exercise program.
SpKt/V increased 11% at the end of the first month of the program (P<.05) and remained elevated for the duration of the program (18%-19%). Distance walked on the 6MWT increased by 14% at both weeks 10 and 20 (P<.05). No changes were noted in KDQOL scores.
A low-intensity intradialytic exercise program is a viable adjunctive therapy, which improves HD efficacy and physical function in HD patients.
确定一项为期20周的透析期间锻炼计划对自我护理血液透析（HD）患者的透析效果、身体机能和生活质量的影响。该计划包括累计时长60分钟的低强度锻炼，在透析的前两小时进行。
单组重复测量。
隶属于一家加拿大教学医院的卫星HD单位。
选取13名自我护理HD患者作为便利样本，这些患者透析情况稳定至少6个月，且经过医学筛查，排除了会妨碍锻炼的严重心脏、肺部和/或肌肉骨骼疾病。
一项为期5个月的透析期间锻炼计划，受试者每周锻炼3次（使用自行车测力计、迷你踏步机），在HD的前两小时各锻炼30分钟。
在锻炼计划的每个月开始前和结束时评估透析效果（采用尿素动力学单池模型[spKt/V]）。在基线以及锻炼计划的第10周和第20周测定身体机能（6分钟步行试验[6MWT]）和生活质量（肾脏病生活质量简表[KDQOL]）。
在计划的第一个月末，spKt/V增加了11%（P<0.05），并且在计划期间一直保持升高（18%-19%）。在第10周和第20周，6MWT的步行距离均增加了14%（P<0.05）。KDQOL评分未发现变化。
低强度的透析期间锻炼计划是一种可行的辅助治疗方法，可改善HD患者的透析效果和身体机能。
