一项关于曲前列尼尔治疗和预防系统性硬化症患者指端溃疡的试点试验。
A pilot trial of treprostinil for the treatment and prevention of digital ulcers in patients with systemic sclerosis.
作者信息
Chung Lorinda, Fiorentino David
机构信息
Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, California 94305, USA.
出版信息
J Am Acad Dermatol. 2006 May;54(5):880-2. doi: 10.1016/j.jaad.2006.02.004.
PMID:16635673
Abstract
We performed a pilot trial of subcutaneous treprostinil for the treatment of digital ulcers in scleroderma. Of the 5 patients completing therapy, ulcer size significantly decreased and no new ulcers occurred on continuous therapy. Although effective, the high rate of injection site reactions may limit the utility of this therapy.
摘要
我们开展了一项皮下注射曲前列尼尔治疗硬皮病指端溃疡的试验性研究。5例完成治疗的患者中，溃疡大小显著减小，持续治疗期间未出现新的溃疡。尽管该疗法有效，但注射部位反应发生率高可能会限制其应用。
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