Shook Brent A, Wells Michael J, Rapini Ronald P, Cobos Everardo
Department of Dermatology, Texas Tech University School of Medicine, Lubbock, Texas 79430, USA.
J Am Acad Dermatol. 2006 May;54(5):888-91. doi: 10.1016/j.jaad.2005.08.020.
We report 2 patients with documented chronic hepatitis C infection and epidermolysis bullosa acquisita (EBA). Both patients clinically represent classic EBA, exhibiting skin fragility and blistering occurring both spontaneously and secondary to trauma, which heal with milia and scar formation. EBA often is a disease of altered immune status and debility. Further work is necessary to show whether hepatitis C plays a causative role in EBA in these 2 patients and in general.
我们报告了2例确诊为慢性丙型肝炎感染且患有获得性大疱性表皮松解症(EBA)的患者。两名患者临床上均表现为典型的EBA,表现出皮肤脆弱性以及自发和外伤后出现的水疱,愈合后有粟丘疹和瘢痕形成。EBA通常是一种免疫状态改变和身体虚弱的疾病。有必要进一步研究丙型肝炎在这2例患者以及总体上是否在EBA中起致病作用。