磁源成像定位结节性硬化症患儿的致痫灶。
Magnetic source imaging localizes epileptogenic zone in children with tuberous sclerosis complex.
作者信息
Wu J Y, Sutherling W W, Koh S, Salamon N, Jonas R, Yudovin S, Sankar R, Shields W D, Mathern G W
机构信息
Division of Pediatric Neurology, The Brain Research Institute, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
出版信息
Neurology. 2006 Apr 25;66(8):1270-2. doi: 10.1212/01.wnl.0000208412.59491.9b.
The authors assessed whether magnetoencephalography/magnetic source imaging (MEG/MSI) identified epileptogenic zones in patients with tuberous sclerosis complex (TSC). In six TSC children with focal seizures, ictal video-EEG predicted the region of resection with 56% sensitivity, 80% specificity, and 77% accuracy (p = 0.02), whereas interictal MEG/MSI fared better (100%, 94%, and 95%, respectively; p < 0.0001). Interictal MEG/MSI seems to identify epileptogenic zones more accurately in children with TSC and focal intractable epilepsy.
作者评估了脑磁图/磁源成像（MEG/MSI）是否能识别结节性硬化症（TSC）患者的致痫区。在6名患有局灶性癫痫发作的TSC儿童中，发作期视频脑电图预测切除区域的敏感度为56%，特异度为80%，准确率为77%（p = 0.02），而发作间期MEG/MSI表现更佳（分别为100%、94%和95%；p < 0.0001）。发作间期MEG/MSI似乎能更准确地识别患有TSC和局灶性难治性癫痫的儿童的致痫区。
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