Pieper Barbara A, Templin Thomas N, Ebright John R
Wayne State University, 5557 Cass Avenue, Detroit, MI 48202, USA.
Ostomy Wound Manage. 2006 Apr;52(4):46-52, 54-6, 58.
Chronic venous insufficiency and subsequent difficulties in leg function are causally linked to injection drug use and quality of life. Because injection drug use is a risk factor for human immunodeficiency virus infection, chronic venous insufficiency would be expected to occur with a higher prevalence in HIV-positive persons, yet the impact of chronic venous insufficiency on quality of life has not been investigated in this population. A cross-sectional design with quota sampling was used to enroll 73 HIV-positive participants-- 46 injection drug users and 27 non-injection drug users -- in this quality-of-life study. Questionnaires were read to participants and their legs were assessed for evidence of chronic venous insufficiency. Leg function scores, comprising assessment of leg pain, interference, and difficulty in using legs, were significantly related (P <.05) to quality-of-life scores, controlling for comorbid health problems. Chronic venous insufficiency, injection drug use, and leg function were interrelated. The legs of HIV-positive persons who have injected drugs should be assessed for manifestations of chronic venous insufficiency and other functional impairments. Further research involving a larger sample and assessment of chronic venous insufficiency treatments, including quality of life and leg function in HIV-positive persons, is needed.
慢性静脉功能不全以及随后出现的腿部功能障碍与注射吸毒及生活质量存在因果关系。由于注射吸毒是人类免疫缺陷病毒感染的一个危险因素，预计慢性静脉功能不全在艾滋病毒阳性者中的患病率会更高，然而，尚未对该人群中慢性静脉功能不全对生活质量的影响进行调查。本生活质量研究采用配额抽样的横断面设计，招募了73名艾滋病毒阳性参与者——46名注射吸毒者和27名非注射吸毒者。向参与者宣读问卷，并对他们的腿部进行评估，以寻找慢性静脉功能不全的证据。在控制合并存在的健康问题的情况下，包括对腿部疼痛、干扰和腿部使用困难的评估在内的腿部功能评分与生活质量评分显著相关（P<.05）。慢性静脉功能不全、注射吸毒和腿部功能相互关联。应对曾注射毒品的艾滋病毒阳性者的腿部进行评估，以检查是否存在慢性静脉功能不全和其他功能障碍的表现。需要开展进一步的研究，纳入更大的样本，并评估慢性静脉功能不全的治疗方法，包括艾滋病毒阳性者的生活质量和腿部功能。
