REES (Réseau d'Evaluation En Economie de la Santé), 28 rue d'Assas, F-75006 Paris, France.
Eur J Vasc Endovasc Surg. 2010 Dec;40(6):783-9. doi: 10.1016/j.ejvs.2010.03.034. Epub 2010 Oct 29.
To review the psychometric validation of the Chronic Venous dIsease quality of life Questionnaire (CIVIQ-20) in the countries that have used it since 1996.
Prospective, clinical, international study in 18 countries.
Patients with venous disease of the lower limb in the clinical, aetiological, anatomical and pathophysiological (CEAP) clinical stages C0s to C4 presenting to surgical outpatient departments and general practices and receiving drug treatment for 6 months.
Quantification of symptoms on a four-point scale and pain on a visual analogue scale, and self-administration of CIVIQ-20 to patients before visit (baseline, 2, 4 and 6 months).
In 3956 patients, CIVIQ-20 showed good internal consistency and reliability (above 0.80) through test-retest correlations. The discriminating power of items was good in known groups of patients. Factor analysis identified physical, psychological and pain factors as important, but revealed instability of the social factor. CIVIQ-20 was highly sensitive to changes in the quality of life of patients clinically improved after drug treatment.
CIVIQ-20 is valuable in assessing treatment effects in longitudinal, multinational studies, but comparisons of different populations should use the global score rather than scores per dimension.
综述自 1996 年以来使用慢性静脉疾病生活质量问卷（CIVIQ-20）的国家对其进行的心理计量学验证。
前瞻性、临床、国际研究，涉及 18 个国家。
下肢静脉疾病患者，处于临床、病因、解剖和病理生理（CEAP）临床分期 C0 至 C4，就诊于外科门诊和普通科，接受 6 个月药物治疗。
使用四点量表量化症状和视觉模拟量表疼痛，并在就诊前（基线、2、4 和 6 个月）让患者自我管理 CIVIQ-20。
在 3956 例患者中，通过测试-重测相关性，CIVIQ-20 显示出良好的内部一致性和可靠性（大于 0.80）。项目的区分能力在已知的患者群体中良好。因子分析确定身体、心理和疼痛因素很重要，但社会因素不稳定。CIVIQ-20 对药物治疗后临床改善的患者生活质量变化非常敏感。
CIVIQ-20 在评估纵向、多国研究中的治疗效果方面很有价值，但不同人群的比较应使用总分而非各维度得分。
