Winston Ken R, Lopez John A, Freeman Jane
Department of Neurosurgery, University of Colorado Health Sciences Center and Children's Hospital, Denver, Colorado, USA.
Pediatr Neurosurg. 2006;42(3):151-5. doi: 10.1159/000091857.
The purpose of this study was to review the clinical features of a group of patients in whom ventricular enlargement was not a manifestation of prolonged CSF shunt obstruction.
Twelve patients who had prolonged symptoms consistent with CSF shunt failure and stable normal ventricular size were demonstrated at the time of surgery to have obstruction of their CSF shunts.
Ventricular enlargement is a common but not sine qua non indicator of CSF shunt failure, even after weeks or months of elevated intracranial pressure, and therefore cannot be relied upon for the diagnosis of CSF shunt failure. Although an increase in ventricular size is usually seen relatively early in the course of shunt malfunction, stable normal ventricular size in patients with symptoms and signs that are consistent with shunt failure can delay the diagnosis with potentially serious adverse consequences.
本研究的目的是回顾一组脑室扩大并非长期脑脊液分流梗阻表现的患者的临床特征。
12例有与脑脊液分流失败相符的长期症状且脑室大小稳定正常的患者，在手术时被证明存在脑脊液分流梗阻。
脑室扩大是脑脊液分流失败的常见但非必要指标，即使在颅内压升高数周或数月后亦是如此，因此不能依靠其来诊断脑脊液分流失败。虽然脑室大小增加通常在分流功能障碍过程中相对较早出现，但有与分流失败相符的症状和体征的患者脑室大小稳定正常可能会延迟诊断，从而带来潜在的严重不良后果。
