Bley T A, Uhl M, Venhoff N, Thoden J, Langer M, Markl M
Medical Physics Section, Department of Diagnostic Radiology, University Hospital Freiburg, Hugstetter Strasse 55, 79106 Freiburg, Germany.
Clin Rheumatol. 2007 Mar;26(3):448-50. doi: 10.1007/s10067-005-0160-7. Epub 2006 Apr 25.
Giant cell arteritis (GCA) is a diagnostic challenge. The correct diagnosis is needed for immediate initiation of corticosteroid treatment since blindness is a dreaded complication. Typically, the superficial cranial arteries are affected by this granulomatous vasculitis of large- and medium-sized arteries. However, GCA is not limited to the cranial arteries. Involvement of various arteries such as the cervical and thoracic arteries can also occur. Here, we report a case of histologically proven GCA with cranial and extracranial involvement. We illustrate the usefulness of a comprehensive vascular high-resolution magnetic resonance imaging examination that combines assessment of mural inflammatory changes of the small temporal and occipital arteries with the evaluation of extracranial vasculature to assist in the difficult non-invasive diagnosis and to determine the extent of this inflammatory disease.
巨细胞动脉炎（GCA）是一项诊断难题。由于失明是一种可怕的并发症，因此需要正确诊断以便立即开始使用皮质类固醇治疗。通常，浅表颅动脉会受到这种大中型动脉的肉芽肿性血管炎影响。然而，GCA并不局限于颅动脉。各种动脉如颈动脉和胸动脉也可能受累。在此，我们报告一例经组织学证实的GCA，同时累及颅内和颅外动脉。我们展示了一种全面的血管高分辨率磁共振成像检查的实用性，该检查结合了对颞浅动脉和枕动脉壁炎症变化的评估以及对颅外血管系统的评估，以协助进行困难的非侵入性诊断并确定这种炎症性疾病的范围。
