人类骨髓移植后出现的局限性硬皮病样病变。一种慢性移植物抗宿主反应。
Localized scleroderma-like lesions after bone marrow transplantation in man. A chronic graft versus host reaction.
作者信息
Van Vloten W A, Scheffer E, Dooren L J
出版信息
Br J Dermatol. 1977 Apr;96(4):337-41. doi: 10.1111/j.1365-2133.1977.tb07126.x.
Abstract
Localized scleroderma-like skin lesions which developed in two children, from 8 to 10 months after successful bone marrow transplantation for aplastic anaemia, showed histopathological features resembling those of scleroderma. This finding, like the animal models described in the literature, provides additional support for the auto-immune nature of scleroderma.
摘要
两名儿童在成功进行再生障碍性贫血骨髓移植后8至10个月出现局限性硬皮病样皮肤病变，其组织病理学特征与硬皮病相似。这一发现与文献中描述的动物模型一样，为硬皮病的自身免疫性质提供了额外支持。
Zotero 插件