Fasano Alfonso, Elia Antonio E, Soleti Francesco, Guidubaldi Arianna, Bentivoglio Anna Rita
Istituto di Neurologia, Università Cattolica del Sacro Cuore, Rome, Italy.
Mov Disord. 2006 Aug;21(8):1217-8. doi: 10.1002/mds.20787.
Punding is a stereotypical behavior in which there is an intense fascination with repetitive handling and examining of mechanical objects, such as taking apart watches and radios or arranging common objects (lining up pebbles, rocks, or other small objects). This disabling condition, different from both obsessive-compulsive disorder and mania, is probably underreported. Punding is thought to be related to dopaminergic stimulation, although only a few observations of this condition in patients with Parkinson's disease (PD) under therapy has been reported. We report a man with PD who developed an unusual, severe, repetitive behavior characterized by spending most of his time on his computer; this abnormal behavior was concomitant with the introduction of L-dopa (400 mg per day) and was not associated to a pattern of chronic inappropriate overuse of dopaminergic medication or other psychiatric symptoms. The patient had the feeling he was forced into a disruptive and unproductive behavior, and he made several attempts to quit without succeeding.
刻板行为是一种典型行为，表现为对反复摆弄和检查机械物品有着强烈的迷恋，比如拆卸手表和收音机，或者整理常见物品（将鹅卵石、岩石或其他小物件排成一排）。这种致残状况不同于强迫症和躁狂症，可能未得到充分报道。尽管仅有少数接受治疗的帕金森病（PD）患者出现这种情况的观察报告，但刻板行为被认为与多巴胺能刺激有关。我们报告了一名患有帕金森病的男子，他出现了一种不寻常的、严重的重复行为，其特征是大部分时间都花在电脑上；这种异常行为与左旋多巴（每天400毫克）的使用同时出现，且与慢性不适当过度使用多巴胺能药物的模式或其他精神症状无关。患者感觉自己被迫陷入一种具有破坏性且无成效的行为中，并且他多次尝试戒除但均未成功。
