Coelho Daniel H, Boey Howard P
Division of Otolaryngology, Yale University School of Medicine, 333 Cedar St., Box 208041, New Haven, CT 06520-8041, USA.
Head Neck. 2006 Jun;28(6):564-6. doi: 10.1002/hed.20391.
Parathyroid cysts are uncommon, frequently asymptomatic lesions of the neck and superior mediastinum. Symptomatic parathyroid cysts are very rare, with roughly only 200 cases reported in the literature. Of these, only nine cases have been reported with recurrent laryngeal nerve (RLN) paralysis
We report a case of a 49-year-old man initially seen with a 6-month history of worsening hoarseness. Physical examination revealed a palpable 3-cm, firm, smooth, nontender mass of the right thyroid lobe. Fiberoscopic laryngoscopy showed right vocal cord immobility consistent with RLN paralysis. After CT and fine-needle aspiration of the mass, the patient underwent a right thyroid lobectomy. During surgery, the recurrent laryngeal nerve was found to be stretched and adherent to a right inferior lobe mass.
Histologic analysis of the surgical specimen revealed a benign parathyroid adenomatous cyst. Postoperatively, the patient's voice improved markedly. This case represents an extremely rare return of function of the RLN after cyst removal.
Parathyroid cysts should be included in the differential diagnosis for vocal fold paralysis.
甲状旁腺囊肿并不常见,是颈部和上纵隔常见的无症状病变。有症状的甲状旁腺囊肿非常罕见,文献中报道的病例约200例。其中,仅有9例报道伴有喉返神经(RLN)麻痹。
我们报告一例49岁男性患者,最初表现为声音嘶哑加重6个月。体格检查发现右侧甲状腺叶可触及一个3厘米大小、质地坚硬、表面光滑、无压痛的肿块。纤维喉镜检查显示右侧声带固定,符合喉返神经麻痹。在对肿块进行CT检查和细针穿刺后,患者接受了右侧甲状腺叶切除术。手术中发现喉返神经被拉伸并附着于右下叶肿块。
手术标本的组织学分析显示为良性甲状旁腺腺瘤性囊肿。术后,患者的声音明显改善。该病例代表了囊肿切除后喉返神经功能极其罕见的恢复。
甲状旁腺囊肿应纳入声带麻痹的鉴别诊断。