• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

甲状旁腺囊肿：对国际文献报道的359例患者的综述

Parathyroid cysts: A review of 359 patients reported in the international literature.

作者信息

Papavramidis Theodosios S, Chorti Angeliki, Pliakos Ioannis, Panidis Stavros, Michalopoulos Antonios

机构信息

1st Propedeutic Department of Surgery, Aristotle University of Thessaloniki, AHEPA University Hospital, Thessaloniki, Greece.

出版信息

Medicine (Baltimore). 2018 Jul;97(28):e11399. doi: 10.1097/MD.0000000000011399.

DOI:10.1097/MD.0000000000011399
PMID:29995785
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6076162/
Abstract

BACKGROUND

Parathyroid cysts are lesions that represent 1-5% of neck masses. They are subdivided into two categories: functioning and non-functioning.The aim of the present review is to give a detailed account of all reported cases of parathyroid cysts in the literature and to analyze statistically the available data.

METHODS

A bibliographic research was performed from 1905 until 2016. A database with the patients' characteristics was made and analyzed statistically.

RESULTS

A total of 218 articles were found, reporting 359 cases of cysts. Mean age of patients was 49.24 y/o and the male/female ratio was 1:1.85. The most common locations were left thyroid lobe (113/358 patients, 31.6%), and superior mediastinum (69/358 patients, 19.3%), while the most common symptoms were neck mass (148/355 patients, 41.7%), compressive symptoms (73/355 patients, 206%) and hyperparathyroidism (62/355 patients, 17.5%). Non-functioning cysts were more frequent (220/357 patients, 61.6%). Regarding dimensions, mean diameter was 4.88 cm. Ultrasound and FNA are used for their diagnosis, while cystic fluid analysis may help the differential diagnosis. Recurrences were mentioned in 27/97 patients (27.8%) with available data. No deaths due to parathyroid cysts were mentioned in the literature.

CONCLUSION

Parathyroid cysts should be taken into consideration in case of parathyroid dysfunction or asymptomatic neck mass. The surgeon's careful manipulations on the cyst are crucial for a definitive treatment.

摘要

背景

甲状旁腺囊肿是占颈部肿块1% - 5%的病变。它们可分为两类：功能性和非功能性。本综述的目的是详细阐述文献中所有报道的甲状旁腺囊肿病例，并对现有数据进行统计分析。

方法

进行了从1905年至2016年的文献研究。建立了一个包含患者特征的数据库并进行统计分析。

结果

共找到218篇文章，报道了359例囊肿病例。患者的平均年龄为49.24岁，男女比例为1:1.85。最常见的部位是左甲状腺叶（113/358例患者，31.6%）和上纵隔（69/358例患者，19.3%），而最常见的症状是颈部肿块（148/355例患者，41.7%）、压迫症状（73/355例患者，20.6%）和甲状旁腺功能亢进（62/355例患者，17.5%）。非功能性囊肿更为常见（220/357例患者，61.6%）。关于尺寸，平均直径为4.88厘米。超声和细针穿刺抽吸活检用于其诊断，而囊液分析可能有助于鉴别诊断。在有可用数据的97例患者中有27例（27.8%）提到有复发情况。文献中未提及因甲状旁腺囊肿导致的死亡病例。

结论

在出现甲状旁腺功能障碍或无症状颈部肿块的情况下，应考虑甲状旁腺囊肿。外科医生对囊肿的仔细操作对于确定性治疗至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d0c/6076162/925cfe88e172/medi-97-e11399-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d0c/6076162/10eab39f7a8c/medi-97-e11399-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d0c/6076162/6b2acb80b050/medi-97-e11399-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d0c/6076162/3f091f5808fd/medi-97-e11399-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d0c/6076162/0cbadac93557/medi-97-e11399-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d0c/6076162/a7b56418bd1f/medi-97-e11399-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d0c/6076162/8768d7cb7e97/medi-97-e11399-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d0c/6076162/f6e09d380172/medi-97-e11399-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d0c/6076162/688c929d2458/medi-97-e11399-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d0c/6076162/13b914167b98/medi-97-e11399-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d0c/6076162/925cfe88e172/medi-97-e11399-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d0c/6076162/10eab39f7a8c/medi-97-e11399-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d0c/6076162/6b2acb80b050/medi-97-e11399-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d0c/6076162/3f091f5808fd/medi-97-e11399-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d0c/6076162/0cbadac93557/medi-97-e11399-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d0c/6076162/a7b56418bd1f/medi-97-e11399-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d0c/6076162/8768d7cb7e97/medi-97-e11399-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d0c/6076162/f6e09d380172/medi-97-e11399-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d0c/6076162/688c929d2458/medi-97-e11399-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d0c/6076162/13b914167b98/medi-97-e11399-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d0c/6076162/925cfe88e172/medi-97-e11399-g011.jpg

相似文献

1
Parathyroid cysts: A review of 359 patients reported in the international literature.甲状旁腺囊肿：对国际文献报道的359例患者的综述
Medicine (Baltimore). 2018 Jul;97(28):e11399. doi: 10.1097/MD.0000000000011399.
2
Giant functioning parathyroid cyst presenting as a retrosternal goitre.表现为胸骨后甲状腺肿的巨大功能性甲状旁腺囊肿。
ANZ J Surg. 2007 Apr;77(4):297-304. doi: 10.1111/j.1445-2197.2007.04037.x.
3
Parathyroid cyst: differential diagnosis.甲状旁腺囊肿：鉴别诊断。
BMJ Case Rep. 2020 Oct 10;13(10):e232017. doi: 10.1136/bcr-2019-232017.
4
Parathyroid cysts.甲状旁腺囊肿。
Am Surg. 1984 Jan;50(1):29-32.
5
Diagnostic and therapeutic review of cystic parathyroid lesions.囊性甲状旁腺病变的诊断和治疗回顾。
Hormones (Athens). 2012 Oct-Dec;11(4):410-8. doi: 10.14310/horm.2002.1372.
6
Parathyroid cysts: a case report and review of the literature.甲状旁腺囊肿：一例病例报告及文献综述
Laryngoscope. 2001 Oct;111(10):1726-8. doi: 10.1097/00005537-200110000-00010.
7
Misdiagnosed giant parathyroid cyst: differential diagnosis of a neck mass of the central region.误诊的巨大甲状旁腺囊肿：中央区域颈部肿块的鉴别诊断。
BMJ Case Rep. 2022 Jun 22;15(6):e245501. doi: 10.1136/bcr-2021-245501.
8
Parathyroid cysts of the neck and mediastinum. Case report.颈部及纵隔甲状旁腺囊肿。病例报告。
Acta Chir Scand. 1989 Mar;155(3):211-6.
9
Parathyroid cysts.甲状旁腺囊肿。
Am J Surg. 1978 Mar;135(3):395-402. doi: 10.1016/0002-9610(78)90073-9.
10
Cystic parathyroid presenting as an apparent thyroid goiter.表现为明显甲状腺肿的甲状旁腺囊肿。
Eur Arch Otorhinolaryngol. 2008 Oct;265(10):1285-8. doi: 10.1007/s00405-008-0608-x. Epub 2008 Feb 26.

引用本文的文献

1
Author's response to Letter to the Editor re: Paz-Ilbarra C-ZM et al. A giant parathyroid cyst causing primary hyperparathyroidism in a pregnant woman: Case report and literature review. 2024: 1-6. DOI: https://doi.org/10.1177/1753495X2412492.作者对致编辑信的回复：关于Paz-Ilbarra C-ZM等人的《巨大甲状旁腺囊肿导致孕妇原发性甲状旁腺功能亢进：病例报告及文献综述》。2024年：第1 - 6页。DOI：https://doi.org/10.1177/1753495X2412492 。
Obstet Med. 2025 Mar 28:1753495X251328111. doi: 10.1177/1753495X251328111.
2
Ultrasound-guided minimally invasive treatment of nonfunctional parathyroid cysts: a description of five cases.超声引导下微创治疗无功能甲状旁腺囊肿：5例病例描述
Quant Imaging Med Surg. 2025 Mar 3;15(3):2658-2665. doi: 10.21037/qims-24-1921. Epub 2025 Feb 26.
3

本文引用的文献

1
Small nonfunctional parathyroid cysts: single institution experience.小型无功能甲状旁腺囊肿：单机构经验
Endocr J. 2017 Feb 27;64(2):151-156. doi: 10.1507/endocrj.EJ16-0398. Epub 2016 Oct 19.
2
Non-functional parathyroid cyst--diagnostic pitfall: A case-report.无功能性甲状旁腺囊肿——诊断陷阱：一例病例报告
Vojnosanit Pregl. 2015 Nov;72(11):1032-4. doi: 10.2298/vsp140624103p.
3
Parathyroid cysts.甲状旁腺囊肿。
Cystic parathyroid lesion: case report of rare entity.甲状旁腺囊性病变：罕见病例报告
Ann Med Surg (Lond). 2025 Jan 9;87(1):413-416. doi: 10.1097/MS9.0000000000002869. eCollection 2025 Jan.
4
Improvement in Recurrent Laryngeal Nerve Paralysis and Tracheal Deviation after Surgical Resection of a Mediastinal Parathyroid Cyst: A Case Report.纵隔甲状旁腺囊肿手术切除后喉返神经麻痹及气管偏移的改善：一例报告
Surg Case Rep. 2025;11(1). doi: 10.70352/scrj.cr.24-0083. Epub 2025 Jan 31.
5
Parathyroid Cyst and Micropapillary Thyroid Carcinoma: A Case Study of Unexpected Concurrent Endocrine Pathologies.甲状旁腺囊肿与甲状腺微小乳头状癌：一例意外并发的内分泌疾病病例研究
Cureus. 2024 Aug 19;16(8):e67208. doi: 10.7759/cureus.67208. eCollection 2024 Aug.
6
Excision of Giant Cervicomediastinal Parathyroid Cyst: Case Report and Literature Review.巨大颈纵隔甲状旁腺囊肿切除术：病例报告及文献综述
Indian J Otolaryngol Head Neck Surg. 2024 Aug;76(4):3632-3636. doi: 10.1007/s12070-024-04655-2. Epub 2024 Apr 16.
7
Mediastinal parathyroid cyst: A case report and review of the literature.纵隔甲状旁腺囊肿：一例病例报告及文献复习
Radiol Case Rep. 2024 Jul 6;19(9):4003-4006. doi: 10.1016/j.radcr.2024.06.049. eCollection 2024 Sep.
8
Hypercalcemic Crisis Due to a Giant Intrathyroidal Parathyroid Adenoma, with Postsurgical Severe Hypocalcemia and Hungry Bone Syndrome: A Case Report.巨大甲状腺内甲状旁腺腺瘤导致的高钙血症危象，术后出现严重低钙血症和饥饿骨综合征：一例报告
Clin Pract. 2024 Jan 22;14(1):179-187. doi: 10.3390/clinpract14010015.
9
Tc-methoxyisobutylisonitrile single-photon emission computed tomography/computed tomography parathyroid imaging in the diagnosis of functional parathyroid cysts: an initial experience.锝-甲氧基异丁基异腈单光子发射计算机断层扫描/计算机断层扫描甲状旁腺成像在功能性甲状旁腺囊肿诊断中的初步经验
Gland Surg. 2024 Jan 29;13(1):32-44. doi: 10.21037/gs-23-273. Epub 2024 Jan 25.
10
A Middle-aged Woman With Recurrent Intrathyroidal Parathyroid Cyst Treated With Ethanol Sclerotherapy.一名接受乙醇硬化治疗的复发性甲状腺内甲状旁腺囊肿中年女性。
AACE Clin Case Rep. 2023 Oct 10;9(6):186-188. doi: 10.1016/j.aace.2023.08.001. eCollection 2023 Nov-Dec.
Am Surg. 2015 Apr;81(4):E163-5.
4
[A case of idiopathic neck bleeding from a parathyroid cyst].[一例甲状旁腺囊肿引起的特发性颈部出血病例]
Nihon Jibiinkoka Gakkai Kaiho. 2014 Sep;117(9):1194-9. doi: 10.3950/jibiinkoka.117.1194.
5
A rare case of a parathyroid adenoma inside a parathyroid cyst.甲状旁腺囊肿内甲状旁腺腺瘤的罕见病例。
Arq Bras Endocrinol Metabol. 2014 Oct;58(7):776-8. doi: 10.1590/0004-2730000003211.
6
[Mediastinal parathyroid cyst - a case report].[纵隔甲状旁腺囊肿——病例报告]
Laeknabladid. 2014 Sep;100(9):453-5. doi: 10.17992/lbl.2014.09.557.
7
A rare cystic lesion of the neck: parathyroid cyst.一种罕见的颈部囊性病变：甲状旁腺囊肿。
BMJ Case Rep. 2013 Oct 11;2013:bcr2013200813. doi: 10.1136/bcr-2013-200813.
8
Hyperparathyroidism caused by a functional parathyroid cyst.功能性甲状旁腺囊肿引起的甲状旁腺功能亢进。
BMJ Case Rep. 2013 Jun 21;2013:bcr2012008290. doi: 10.1136/bcr-2012-008290.
9
Multiple functional parathyroid cysts.多发性功能性甲状旁腺囊肿。
J Clin Endocrinol Metab. 2013 Jul;98(7):2641-2. doi: 10.1210/jc.2013-1743. Epub 2013 May 10.
10
Thoracoscopic resection of a giant mediastinal parathyroid cyst.胸腔镜下巨大纵隔甲状旁腺囊肿切除术
Gen Thorac Cardiovasc Surg. 2014 Jul;62(7):444-50. doi: 10.1007/s11748-013-0256-y. Epub 2013 Apr 27.