Turner Joy L, Fielding James E, Clothier Hazel J, Kelly Heath A
Epidemiology Unit, Victorian Infectious Diseases Reference Laboratory, Melbourne, Victoria.
Commun Dis Intell Q Rep. 2006;30(1):137-43.
Influenza activity remained within normal seasonal activity with a well-defined peak at week 29 (beginning 18 July) during the Victorian influenza season from May to September 2005. Surveillance was based on sentinel general practice influenza-like illness (ILI) notifications with laboratory confirmation, medical locum service ILI notifications and laboratory notification of influenza detections. One thousand and eighty-seven consultations for ILI were reported from 38 general practices, while medical practitioners from the locum service reported 317 consultations for ILI. The average weekly rate of ILI from sentinel surveillance was 7.3 per 1,000 consultations. Similar numbers of influenza A subtypes H1N1 and H3N2 were detected; 45 per cent of which were A/California/7/2004-like (H3), 44 per cent were A/New Caledonia/20/99-like (H1) and 11 per cent were A/Wellington/1/2004 (H3). Of the influenza B samples, 67 per cent were B/Hong Kong/330/2001-like and 33 per cent were B/Shanghai/361/2002-like. The influenza vaccine for 2005 contained: A/New Caledonia/20/99(H1N1)-like virus, A/Wellington/ 1/2004(H3N2)-like virus, and B/Shanghai/361/2002-like virus. Although the predominant H3 and B circulating strains were not included in the vaccine, there was reasonable serological cross protection between vaccine and circulating strains.
在2005年5月至9月的维多利亚州流感季节期间,流感活动维持在正常季节性活动范围内,在第29周(7月18日开始)出现了一个明确的高峰。监测基于定点全科医生流感样疾病(ILI)通报并经实验室确认、医疗临时服务的ILI通报以及流感检测的实验室通报。38家全科诊所报告了1087例ILI会诊,而临时服务的医生报告了317例ILI会诊。定点监测的ILI平均每周发病率为每1000次会诊7.3例。检测到的甲型流感亚型H1N1和H3N2数量相似;其中45%为A/加利福尼亚/7/2004样株(H3),44%为A/新喀里多尼亚/20/99样株(H1),11%为A/惠灵顿/1/2004(H3)。在乙型流感样本中,67%为B/香港/330/2001样株,33%为B/上海/361/2002样株。2005年的流感疫苗包含:A/新喀里多尼亚/20/99(H1N1)样病毒、A/惠灵顿/1/2004(H3N2)样病毒和B/上海/361/2002样病毒。尽管疫苗中未包含主要流行的H3和B毒株,但疫苗与流行毒株之间存在合理的血清学交叉保护。