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2017年澳大利亚维多利亚州流感季严重,以甲型(H3N2)流感为主。

A severe 2017 influenza season dominated by influenza A(H3N2), Victoria, Australia.

作者信息

Grant K A, Carville K S, Sullivan S G, Strachan J, Druce J, Fielding J E

机构信息

Victorian Infectious Diseases Reference Laboratory, Melbourne, Australia.

WHO Collaborating Centre for Reference and Research on Influenza, Melbourne, Australia.

出版信息

Western Pac Surveill Response J. 2018 Sep 28;9(5 Suppl 1):18-26. doi: 10.5365/wpsar.2018.9.5.010. eCollection 2018 Winter.

DOI:10.5365/wpsar.2018.9.5.010
PMID:31832250
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6902654/
Abstract

Surveillance for influenza-like illness (ILI) and laboratory-confirmed influenza in Victoria, Australia is undertaken jointly by the Victorian Infectious Diseases Reference Laboratory and the Victorian Government Department of Health and Human Services from May to October each year. Surveillance data comprise notifiable laboratory-confirmed influenza and ILI reporting from from two sources - a general practice sentinel surveillance programme and a locum service. The magnitude of the 2017 influenza season was high in Victoria with widespread circulation of influenza type A(H3N2), which peaked in September. A record number of laboratory-confirmed influenza cases were notified, and the proportion of ILI cases to total consultations from both the general practice and locum service were higher than previous years. Notified cases of influenza A were older than influenza B cases with 25% compared to 17% aged more than 65 years, respectively. The proportion of swabs that were positive for influenza peaked at 58%. Antigenic characterization suggested a good match between the circulating and vaccine strains of influenza A(H3N2). Most of the increases observed in notified cases of laboratory-confirmed influenza in recent years in Victoria have been attributed to increases in testing. However, that cases of ILI also increased in Victoria in 2017 is suggestive that 2017 was a relatively severe season. The dominance of influenza type A(H3N2), the extended duration of elevated activity, and a potential phylogenetic mismatch of vaccine to circulating strains are likely to have contributed to the relative severity of the 2017 season. Victoria is Australia's second most populous state and is the mainland's southernmost state. It has a temperate climate with an influenza season usually occurring in the cooler months between May and October. The Victorian Infectious Diseases Reference Laboratory (VIDRL), in partnership with the Victorian Government Department of Health and Human Services (DHHS), coordinates influenza-like illness (ILI) and laboratory-confirmed influenza surveillance in Victoria. There are three data sources included in the influenza surveillance system.

摘要

澳大利亚维多利亚州的流感样疾病(ILI)监测以及实验室确诊流感监测工作,每年5月至10月由维多利亚传染病参考实验室与维多利亚州卫生与公众服务部联合开展。监测数据包括来自两个来源的法定报告实验室确诊流感和ILI报告——一个全科医生哨点监测项目和一个临时替班服务。2017年维多利亚州流感季规模较大,甲型(H3N2)流感广泛传播,9月达到高峰。报告的实验室确诊流感病例数量创纪录,全科医生和临时替班服务中ILI病例占总会诊的比例高于往年。报告的甲型流感病例比乙型流感病例年龄更大,65岁以上的患者分别占25%和17%。流感检测呈阳性的拭子比例最高达到58%。抗原特性表明,甲型(H3N2)流感的流行毒株与疫苗毒株匹配良好。近年来维多利亚州报告的实验室确诊流感病例增加,多数归因于检测增加。然而,2017年维多利亚州ILI病例也增加,这表明2017年是一个相对严重的季节。甲型(H3N2)流感占主导、活动水平升高的持续时间延长以及疫苗与流行毒株可能存在系统发育不匹配,可能导致了2017年流感季相对严重。维多利亚州是澳大利亚人口第二多的州,也是大陆最南端的州。其气候温和,流感季通常发生在5月至10月较凉爽的月份。维多利亚传染病参考实验室(VIDRL)与维多利亚州卫生与公众服务部(DHHS)合作,在维多利亚州协调流感样疾病(ILI)和实验室确诊流感监测。流感监测系统包括三个数据来源。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9154/6902654/b785f5352b42/wpsar.2018.9.5-024-F6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9154/6902654/c68c7e50613b/wpsar.2018.9.5-021-F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9154/6902654/ead099568cab/wpsar.2018.9.5-021-F2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9154/6902654/fae80f5e6389/wpsar.2018.9.5-022-F3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9154/6902654/84c3037b0c93/wpsar.2018.9.5-022-F4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9154/6902654/f0e4fd8dee1e/wpsar.2018.9.5-023-F5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9154/6902654/b785f5352b42/wpsar.2018.9.5-024-F6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9154/6902654/c68c7e50613b/wpsar.2018.9.5-021-F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9154/6902654/ead099568cab/wpsar.2018.9.5-021-F2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9154/6902654/fae80f5e6389/wpsar.2018.9.5-022-F3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9154/6902654/84c3037b0c93/wpsar.2018.9.5-022-F4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9154/6902654/f0e4fd8dee1e/wpsar.2018.9.5-023-F5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9154/6902654/b785f5352b42/wpsar.2018.9.5-024-F6.jpg

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