Sukhodolets V V
Mol Biol (Mosk). 2006 Mar-Apr;40(2):369-71.
In the process of DNA replication in Escherichia coli, the unequal crossing over occurs between DNA direct repeats in sister chromosomes. Such exchanges lead to the formation of tandem duplications and, therefore, to an increase of gene expression. It is proposed that non-homologous cohesion of sister chromosomes and unequal crossing over occur if the movement of replication fork is stopped. In the case of the unceasing movement of replication fork the homologous exchange between sister chromosomes occurs which provides their post-replication reparation.
在大肠杆菌的DNA复制过程中，姐妹染色单体中的DNA直接重复序列之间会发生不等交换。这种交换导致串联重复的形成，从而导致基因表达增加。有人提出，如果复制叉的移动停止，姐妹染色单体就会发生非同源黏连和不等交换。在复制叉持续移动的情况下，姐妹染色单体之间会发生同源交换，从而实现复制后的修复。
