[研究大肠杆菌中杂合串联重复序列的重组]
[Studying recombination in heterozygous tandem duplications in Escherichia coli].
作者信息
Prokop'ev V V, Sukhodolets V V
出版信息
Genetika. 2007 Apr;43(4):570-4.
PMID:17555136
Abstract
Our previous data showed that the principal pathway of the formation of selected recombinants in Escherichia coli strains carrying heterozygous tandem duplications is unequal crossing over between sister chromosomes. Data presented in this work showed that when DNA homology is not disturbed (due to transposon insertion), intragenic recombinants can occur directly in the region of recombination through intrachromomal exchange as well.
摘要
我们之前的数据表明，在携带杂合串联重复的大肠杆菌菌株中，选定重组体形成的主要途径是姐妹染色单体之间的不等交换。这项工作中呈现的数据表明，当DNA同源性未受干扰时（由于转座子插入），基因内重组体也可通过染色体内交换直接在重组区域发生。
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