Nikolov A, Staĭkov I, Tsankova Ts, Dimitrov A, Stamenova P
Akush Ginekol (Sofiia). 2006;45(2):49-52.
Fhlebothrombosis and thrombophlebitis of the cerebral veins and sinuses develop relatively rare, but they affect young people and have poor prognosis. Pregnancy and puerperium are et risk due to hormonal and homeostatic changes in the organism. This report exhibits the most frequent etiologic factor, early symptoms, clinical manifestation, diagnostic value of the different methods, treatment principals and the factors that determine the outcome of thrombofphlebitis and phlebothrombosis during pregnancy and puerperium. In the acute phase a treatment with direct anticoagulants (intravenous heparin or low molecular mass heparins) and symptomatic treatment with anticonvulsants and drugs against oedema. After the acute phase the treatment continues with oral indirect anticoagulant as long as the severity of the disease requires.
脑静脉和静脉窦的血栓形成和血栓性静脉炎相对少见,但影响年轻人且预后较差。妊娠和产褥期因机体激素和内环境变化而处于风险中。本报告展示了妊娠和产褥期血栓性静脉炎和血栓形成最常见的病因、早期症状、临床表现、不同方法的诊断价值、治疗原则以及决定其预后的因素。急性期采用直接抗凝剂(静脉注射肝素或低分子肝素)治疗,并对症使用抗惊厥药和抗水肿药物。急性期过后,只要疾病严重程度需要,就继续使用口服间接抗凝剂进行治疗。