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[新生儿短暂性呼吸急促、产科及新生儿危险因素]

[Transient tachypnea of the newborn, obstetric and neonatal risk factors].

作者信息

Pérez Molina J Jesús, Romero Diana Maria Carlos, Ramírez Valdivia Juan Manuel, Corona Moisés Quiles

机构信息

División de Pediatría del Hospital Civil de Guadalajara Dr Juan I Menchaca y Departamento de Clínicas de la Reproducción Humana, México.

出版信息

Ginecol Obstet Mex. 2006 Feb;74(2):95-103.

PMID:16637378
Abstract

OBJECTIVE

To identify the obstetrics and neonatal risk factors associated with transient tachypnea of the newborn.

PATIENTS AND METHODS

Case-control study of 110 neonates with transient tachypnea and 110 newborns controls, between May and October 2000, in the Hospital Civil de Guadalajara Dr. Juan I. Menchaca. The diagnosis of transient tachypnea was done by clinical and radiology data and exclusion of the other causes of respiratory distress. The exposure was documented by a direct interview to the mother and clinical information of the clinical expedient. The association was measured with the odds ratios and confidence interval of 95%.

RESULTS

The frequency of transient tachypnea was of 2 percent newborn alive. The risk factors that were associated with transient tachypnea was: low Apgar score at minute (OR: 33.74, CI 95%: 4.73-681.52), premature rupture of amniotic membranes (OR: 3.65, CI 95%: 1.53-8.90), cesarean section (OR: 2.01, CI 95%: 1.14-3.57) and masculine gender (OR: 2.02, CI 95%: 1.14-3.60). It was more frequent in the cases the antecedent of diabetes mellitus and bronchial asthma.

CONCLUSIONS

The results suggest that it's necessary to improve the obstetrics surveillance to diminish the frequency of low Apgar score and risk factors associated with transient tachypnea of the newborn.

摘要

目的

确定与新生儿短暂性呼吸急促相关的产科和新生儿危险因素。

患者与方法

2000年5月至10月期间,在瓜达拉哈拉市胡安·I·门查卡公民医院对110例患有短暂性呼吸急促的新生儿和110例新生儿对照进行病例对照研究。通过临床和放射学数据以及排除其他呼吸窘迫原因来诊断短暂性呼吸急促。通过对母亲的直接访谈和临床病历的临床信息记录暴露情况。用比值比和95%置信区间来衡量关联性。

结果

存活新生儿中短暂性呼吸急促的发生率为2%。与短暂性呼吸急促相关的危险因素有:1分钟时阿氏评分低(比值比:33.74,95%置信区间:4.73 - 681.52)、胎膜早破(比值比:3.65,95%置信区间:1.53 - 8.90)、剖宫产(比值比:2.01,95%置信区间:1.14 - 3.57)以及男性(比值比:2.02,95%置信区间:1.14 - 3.60)。糖尿病和支气管哮喘病史在病例中更常见。

结论

结果表明有必要改善产科监测,以降低低阿氏评分的频率以及与新生儿短暂性呼吸急促相关的危险因素。

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