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[小脑血肿。基于治疗态度的队列描述及预后]

[Cerebellar hematomas. Description of a cohort and prognosis based on therapeutic attitude].

作者信息

Virgós-Señor B, Nebra-Puertas A C, Villagrasa-Compaired J, Van Popta J

机构信息

Servicio de Medicina Intensiva, Hospital Universitario Miguel Servet, Zaragoza, España.

出版信息

Med Intensiva. 2006 Jan-Feb;30(1):1-5. doi: 10.1016/s0210-5691(06)74454-0.

DOI:10.1016/s0210-5691(06)74454-0
PMID:16637424
Abstract

OBJECTIVES

Spontaneous cerebellar hematomas (CH) represent 5%-10% of intracranial hemorrhaging. We describe the existing cardiovascular risk factors, clinical presentation of CH and its relationship with mortality and the association between the treatment type (conservative medical or neurosurgical treatment) and the subsequent course of the patients.

DESIGN AND SCOPE

Observational study of patients diagnosed of CH admitted over three years in an Intensive Care Unit of a level III Hospital.

PATIENTS

Fifty-six consecutive patients diagnosed of CH. VARIABLES OF PRINCIPAL INTEREST: We studied the cardiovascular risk factors, presentation form (with Glasgow Coma Scale- GCS), hematoma size and site, and morbidity-mortality of the patients (with the Glasgow Outcome Scale--GOS).

RESULTS

Fisher's exact test, Chi squared, calculation of Spearman's coefficient between certain variables and logistic regression analysis were used. Hematoma size, GCS on admission and presence of hydrocephaly obtained statistical significance. Conservative medical treatment has greater mortality.

CONCLUSIONS

Patients with GCS < or = 8 and hematoma size > or = 3 cm benefit from surgical treatment. Initial GCS and vermian site are mortality predictor factors. There is no more morbidity due to surgical treatment.

摘要

目的

自发性小脑血肿(CH)占颅内出血的5%-10%。我们描述了现有的心血管危险因素、CH的临床表现及其与死亡率的关系,以及治疗类型(保守药物治疗或神经外科治疗)与患者后续病程之间的关联。

设计与范围

对一家三级医院重症监护病房三年内收治的诊断为CH的患者进行观察性研究。

患者

56例连续诊断为CH的患者。主要关注变量:我们研究了心血管危险因素、表现形式(采用格拉斯哥昏迷量表-GCS)、血肿大小和部位,以及患者的发病率和死亡率(采用格拉斯哥预后量表-GOS)。

结果

采用Fisher精确检验、卡方检验、某些变量之间的Spearman系数计算以及逻辑回归分析。血肿大小、入院时的GCS和脑积水的存在具有统计学意义。保守药物治疗的死亡率更高。

结论

格拉斯哥昏迷量表评分≤8分且血肿大小≥3 cm的患者从手术治疗中获益。初始格拉斯哥昏迷量表评分和蚓部部位是死亡率的预测因素。手术治疗不会增加更多的发病率。

相似文献

1
[Cerebellar hematomas. Description of a cohort and prognosis based on therapeutic attitude].[小脑血肿。基于治疗态度的队列描述及预后]
Med Intensiva. 2006 Jan-Feb;30(1):1-5. doi: 10.1016/s0210-5691(06)74454-0.
2
Management of spontaneous cerebellar hematomas: a prospective treatment protocol.自发性小脑血肿的管理:一项前瞻性治疗方案。
Neurosurgery. 2001 Dec;49(6):1378-86; discussion 1386-7. doi: 10.1097/00006123-200112000-00015.
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A prospective study of a series of 356 patients with supratentorial spontaneous intracerebral haematomas treated in a Neurosurgical Department.对神经外科治疗的一系列356例幕上自发性脑内血肿患者进行的前瞻性研究。
Acta Neurochir (Wien). 2005 Aug;147(8):823-9. doi: 10.1007/s00701-005-0531-5. Epub 2005 Jun 23.
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[Primary intracerebellar hematomas: surgical indications, prognosis].[原发性小脑血肿:手术指征、预后]
Chirurgia (Bucur). 2010 Nov-Dec;105(6):805-7.
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Predictors of poor outcome in patients with a spontaneous cerebellar hematoma.自发性小脑出血患者预后不良的预测因素。
Can J Neurol Sci. 2000 Feb;27(1):32-6. doi: 10.1017/s0317167100051945.
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[Cerebellar hematomas: a surgically treatable stroke].[小脑血肿:一种可手术治疗的中风]
Rev Neurol. 2000;31(12):1119-26.
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Antiplatelet therapies are associated with hematoma enlargement and increased mortality in intracranial hemorrhage.抗血小板治疗与颅内出血血肿扩大和死亡率增加相关。
Med Intensiva. 2012 Nov;36(8):548-55. doi: 10.1016/j.medin.2012.01.004. Epub 2012 Mar 3.
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Clinical outcome of the patients treated surgically for spontaneous intracerebral hematoma at Sawanpracharak Hospital.沙婉普拉差医院手术治疗自发性脑出血患者的临床结局
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[Spontaneous hematomas of the cerebellum over the age of 60 years].
Neurochirurgie. 1996;42(3):162-7; discussion 167-8.
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Spontaneous cerebellar hemorrhage: clinical remarks on 50 cases.自发性小脑出血:50例临床分析
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引用本文的文献

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Platelet count and early outcome in patients with spontaneous cerebellar hemorrhage: a retrospective study.自发性小脑出血患者的血小板计数与早期预后:一项回顾性研究
PLoS One. 2015 Mar 17;10(3):e0119109. doi: 10.1371/journal.pone.0119109. eCollection 2015.