Pecka M
II. interní klinika Lékarské fakulty UK a FN, Hradec Králové.
Vnitr Lek. 2006 Mar;52 Suppl 1:26-30.
A number of tests can be employed in monitoring anticoagulant, thrombolytic and antiaggregation treatment. Not all, however, indicate precisely the therapeutic effect of the drug used. Some of them are of linear character and they monitor closely the dosage, others have a series of non-specific reactions and the therapeutic effect is largely influenced by these circumstances. This article describes the individual monitoring systems, it deals with their potential reliability issues, and, also, treatment monitoring issues in various diagnostic environments are discussed.
有许多检测方法可用于监测抗凝、溶栓和抗聚集治疗。然而,并非所有检测都能准确表明所用药物的治疗效果。其中一些检测具有线性特征,能密切监测剂量,另一些则有一系列非特异性反应,治疗效果在很大程度上受这些情况影响。本文介绍了各个监测系统,探讨了它们潜在的可靠性问题,还讨论了不同诊断环境下的治疗监测问题。