Lip G Y H, Boos C J
Haemostasis, Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham B18 7QH, UK.
Postgrad Med J. 2008 May;84(991):252-8. doi: 10.1136/hrt.2005.066944.
Atrial fibrillation (AF) can significantly increase morbidity and mortality. It is gaining in clinical and economic importance, being the most commonly encountered tachyarrhythmia in clinical practice. Stroke is the most serious complication. Evidence from AF antithrombotic treatment trials is reviewed, risk stratification of patients with AF is discussed, and recommendations for anticoagulation are presented.
心房颤动(AF)可显著增加发病率和死亡率。它在临床和经济方面的重要性日益增加,是临床实践中最常见的快速性心律失常。中风是最严重的并发症。本文回顾了房颤抗栓治疗试验的证据,讨论了房颤患者的风险分层,并提出了抗凝建议。