Hou H M, Sam K, Hägg U, Rabie A B M, Bendeus M, Yam L Y C, Ip M S
Faculty of Dentistry, The University of Hong Kong, Prince Philip Dental Hospital, 34 Hospital Road, Hong Kong SAR, People's Republic of China.
Angle Orthod. 2006 May;76(3):432-40. doi: 10.1043/0003-3219(2006)076[0432:LDCICO]2.0.CO;2.
The objective of this study was to evaluate long-term dentofacial changes in Chinese obstructive sleep apnea (OSA) patients treated with a mandibular advancement device (MAD). Lateral cephalograms in natural head posture were obtained from 67 consecutive OSA patients (mean age = 46.9 +/- 8.9 years) treated with an MAD. The cephalograms were obtained at start of treatment (T0), after 1 year (T1), 2 years (T2), and 3 years (T3) of treatment. The lateral cephalograms were digitized twice, and the average of two readings was used for statistical analyses. Small, but statistically significant changes occurred in some dentofacial variables. The lower anterior facial height steadily increased during the observation period, and this increase was significant for the T0-T1 and T1-T2 periods and marginally significant for the T2-T3 period. A significant increase in the mandibular plane angle was observed during the T0-T1 and T2-T3 periods only. Significant reductions in the overjet and overbite were observed for the T0-T1 period but not thereafter. Statistically significant dentofacial changes were observed in this study, but they were of small magnitude. The overjet and overbite changes observed mainly occurred at the initial stage of treatment.
本研究的目的是评估使用下颌前移装置（MAD）治疗的中国阻塞性睡眠呼吸暂停（OSA）患者的长期牙颌面变化。从连续67例接受MAD治疗的OSA患者（平均年龄 = 46.9 +/- 8.9岁）获取自然头位时的头颅侧位片。在治疗开始时（T0）、治疗1年（T1）、2年（T2）和3年（T3）时获取头颅侧位片。头颅侧位片数字化两次，取两次读数的平均值用于统计分析。一些牙颌面变量发生了小但具有统计学意义的变化。在观察期内，下颌前部面部高度稳步增加，在T0 - T1期和T1 - T2期增加显著，在T2 - T3期增加不显著。仅在T0 - T1期和T2 - T3期观察到下颌平面角显著增加。在T0 - T1期观察到覆盖和覆牙合显著减小，但此后未观察到。本研究观察到具有统计学意义的牙颌面变化，但变化幅度较小。观察到的覆盖和覆牙合变化主要发生在治疗初期。
